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Pseudoprogression of cutaneous squamous cell carcinoma invading the super vermillion border following programmed death-1 inhibitor monotherapy. | LitMetric

AI Article Synopsis

  • A 55-year-old woman had a skin cancer on her upper lip and started treatment with a medicine called Cemiplimab.
  • At first, her cancer seemed to get worse and new swelling appeared, but after five treatments, she was completely cured with no side effects.
  • This shows that immunotherapy can be really helpful for skin cancer, but sometimes it looks like the cancer is growing even when it is actually improving, which is called pseudoprogression.

Article Abstract

A 55-year-old woman with a moderately differentiated cutaneous squamous cell carcinoma (cSCC) of the upper lip experienced initial tumour growth and new lymphadenopathy after starting immunotherapy with Cemiplimab, but achieved complete remission with no adverse events after five infusions. This case underscores the potential of immunotherapy for cSCC in sensitive head and neck areas and illustrates the phenomenon of pseudoprogression, where apparent tumour growth can occur before clinical improvement.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11297434PMC
http://dx.doi.org/10.1002/ski2.400DOI Listing

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