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An Atypical Spindle Cell/Pleomorphic Lipomatous Tumor of the Thigh With a Difficult Imaging Diagnosis That Mimicked a Malignant Lipomatous Tumor. | LitMetric

AI Article Synopsis

  • Atypical spindle cell/pleomorphic lipomatous tumor is generally classified as a benign tumor, but can be confusing to diagnose due to varying MRI findings.
  • In this case, imaging suggested a potential atypical lipomatous tumor or liposarcoma, leading to a wide resection after a needle biopsy showed benign to low-grade malignancy.
  • The final diagnosis was confirmed through detailed histopathology techniques, highlighting the importance of tissue analysis over imaging alone for accurate diagnosis.

Article Abstract

Atypical spindle cell/pleomorphic lipomatous tumor is categorized as a benign lipomatous tumor, but various MRI findings pose accurate diagnostic challenges. In our case, both MRI and PET/CT scans indicated the possibility of atypical lipomatous tumor/well-differentiated liposarcoma or dedifferentiated liposarcoma. Needle biopsy suggested benign to low-grade malignancy; hence, we opted for the wide resection. The final diagnosis of atypical spindle cell/pleomorphic lipomatous tumor was confirmed through histopathology analysis, including immunohistochemistry and fluorescence in situ hybridization. Since achieving an accurate diagnosis solely through imaging can be challenging, histopathology remains essential.

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Source
http://dx.doi.org/10.1097/RLU.0000000000005271DOI Listing

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