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http://dx.doi.org/10.1007/s12032-024-02460-z | DOI Listing |
Toxicol Sci
December 2024
Nonclinical Drug Safety and Pharmacokinetics Dynamics Metabolism and Bioanalysis, Preclinical Development, Merck & Co. Inc, Rahway, New Jersey, USA.
Clin Chem
December 2024
Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, United States.
J Antimicrob Chemother
January 2025
Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.
JAMA
January 2025
Department of Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia.
Importance: Polygenic risk scores (PRSs) for coronary heart disease (CHD) are a growing clinical and commercial reality. Whether existing scores provide similar individual-level assessments of disease susceptibility remains incompletely characterized.
Objective: To characterize the individual-level agreement of CHD PRSs that perform similarly at the population level.
Ann Transl Med
October 2024
ICU Department, CHU UCL Godinne Namur, UCL Louvain Medical School, Yvoir, Belgium.
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