Humidification and dehumidification are among the most important desalination technologies, in which humidifiers and dehumidifiers are the key components. Previous research has mainly focused on overall system improvement, but few studies have focused on the thermodynamic limitations of the humidification and dehumidification processes. By introducing temperature and enthalpy effectiveness, the thermodynamic limits have been explored. It was successfully established that there are three operating states for the humidifier and dehumidifier. The analytical expressions of enthalpy and temperature effectiveness boundary values in each state were obtained. The results of visualizing the influence of mass flow ratio, inlet temperature, inlet and outlet relative humidity, and pressure on the feasible range of enthalpy and temperature effectiveness were presented. This study explores the thermodynamic limits of heat and mass transfer equipment that can be applied to other types of humidification and dehumidification equipment.
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http://dx.doi.org/10.1016/j.isci.2024.110277 | DOI Listing |
Nat Commun
December 2024
Department of Biomedical Engineering, Pennsylvania State University, University Park, PA, USA.
Over 80% of biologic drugs, and 90% of vaccines, require temperature-controlled conditions throughout the supply chain to minimize thermal inactivation and contamination. This cold chain is costly, requires stringent oversight, and is impractical in remote environments. Here, we report chemical dispersants that non-covalently solvate proteins within fluorous liquids to alter their thermodynamic equilibrium and reduce conformational flexibility.
View Article and Find Full Text PDFJ Chem Inf Model
December 2024
Dipartimento di Bioscienze, Università degli Studi di Milano, Milan 20133, Italy.
The computational study of ligand binding to a target protein provides mechanistic insight into the molecular determinants of this process and can improve the success rate of drug design. All-atom molecular dynamics (MD) simulations can be used to evaluate the binding free energy, typically by thermodynamic integration, and to probe binding mechanisms, including the description of protein conformational dynamics. The advantages of MD come at a high computational cost, which limits its use.
View Article and Find Full Text PDFArch Razi Inst
June 2024
Department of Biotechnology and Microbiology, Karnatak University, Dharwad (Karnataka, India).
Lipases are triacylglycerol hydrolases with various potential applications because of their different physical properties. Most lipase producers are extracellular in nature and are created using solid-state fermentation and submerged fermentation methods. The fungal, mycelial, and yeast lipases are produced using various solid substrates through the solid-state fermentation method.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
December 2024
Department of Assisted Reproduction, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Techniques for sperm cryopreservation have exhibited their potential in male fertility preservation. The use of frozen-thawed sperm in fertilization (IVF) cycles is widespread today. However, many studies reported that cryopreservation might have adverse effects on sperm DNA integrity, motility, and fertilization, probably due to cold shock, intra- and extracellular ice crystals, and excess reactive oxygen species (ROS).
View Article and Find Full Text PDFJACS Au
December 2024
Laboratory of Energy Science and Engineering, Department of Mechanical and Process Engineering, Eidgenössische Technische Hochschule (ETH) Zürich, 8092 Zürich, Switzerland.
There is an urgent need for inexpensive, functional materials that can capture and release CO under industrial conditions. In this context, MgO is a highly promising, earth-abundant CO sorbent. However, despite its favorable carbonation thermodynamics and potential for high gravimetric CO uptakes, MgO-based CO sorbents feature slow carbonation kinetics, limiting their CO uptake during typical industrial contact times.
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