Acute poisoning in children is a major public health problem worldwide. Children poisoning ranks among the top unintentional injuries in children aged less than four years. This paper aimed to describe the pattern and characteristics of acute poisoning incidents, estimate the percentage of medication poisoning among those children and highlight the possible risk factors. All children aged below 10 years admitted to Alexandria Poison Centre (APC) with acute poisoning from the July 1, 2022, to December 31, 2022, were included in the study. A pre-designed structured interviewing questionnaire was used to collect data: socio-demographic data of the poisoned child and his/her caregiver, medical history of the poisoned child and family members, history of previous poisoning incidents in the family, details of the poisoning incident including causative agent, route of poisoning, scene of poisoning, time interval to reach APC and the first aid done. 350 children admitted to APC were included in our study, of which 59% (n=208) of poisoned children were males with mean age 3.14 ± 2.28 years. The types of poisoning found were 46.6% chemical compounds, 31.4% medication, 18% household and 4% food poisoning. Most of the children were poisoned orally. High education of caregiver, urban residence and the presence of chronic disease within a family member were significantly associated with medication poisoning while low education of caregiver, drug addiction, having chronic disease among a family member and the presence of previous poisoning accident in the family were significantly associated with poisoning with chemical compounds. The study found that acute poisoning is more common among young male children in Alexandria; the chemical compounds came first as the main source of poisoning followed by the medication poisoning.
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http://dx.doi.org/10.7759/cureus.63720 | DOI Listing |
Aust Vet J
January 2025
Melbourne Veterinary School, University of Melbourne, Werribee, Victoria, Australia.
Background: PAPP is widely used in Australia as a potent vertebrate bait, with potential for off-target ingestion and poisoning in domestic dogs. Whilst toxicosis and resulting methaemoglobinaemia is anecdotally known to occur, this is the first description in the literature. This study reports thirteen clinical cases of suspected Para-aminopropiophenone (PAPP) toxicity in dogs, with the aim of describing clinical presentation and current management of toxicosis in this species.
View Article and Find Full Text PDFPlants (Basel)
January 2025
Department of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.
The aim of our research was to understand the impact of ochratoxin A (OTA) exposure on various physiological and behavioral aspects in adult Wistar rats, and to evaluate the efficacy of a essential oil (EOC) treatment in restoring the damage caused by this toxin. The essential oils were extracted by hydrodistillation, a yield of 12.70% was obtained for EOC, and the GC-MS characterization of this essential oil revealed that its principal major components are eugenol (80.
View Article and Find Full Text PDFNurs Open
January 2025
Department of Nursing II, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Donostia-San Sebastián, Gipuzkoa, Spain.
Aim: To analyse the association between gender and in-hospital mortality odds ratios among patients in the Basque Country.
Design: Cross-sectional study.
Methods: Admission data pertaining to the period between 1 January 2016 and 31 December 2018 were gathered for all registered acute care hospitals (both public and private) in the Basque Country.
J Pharm Biomed Anal
December 2024
Department of Chemistry, Biochemistry and Physics, South Dakota State University, Box 2202, Brookings, SD 57007, USA. Electronic address:
Organophosphorus (OP) pesticides (e.g., parathion) and nerve agents (e.
View Article and Find Full Text PDFTaiwan J Obstet Gynecol
January 2025
Department of Emergency Medicine, MacKay Memorial Hospital, Taipei 10449, Taiwan; Department of Medicine, MacKay Medical College, New Taipei City, Taiwan; Toxicology Division, Department of Emergency Medicine, MacKay Memorial Hospital, Taipei 10449, Taiwan; Department of Nursing, Yuanpei University of Medical Technology, Hsinchu, Taiwan; MacKay Junior College of Medicine Nursing and Management, Taipei, Taiwan. Electronic address:
Objective: Bongkrekic acid (BKA) is a life-threatening toxin linked to foodborne illnesses. Herein, we report two fatalities among 33 patients who ingested BKA in March 2024, East Taipei, Taiwan.
Case Report: Our first case involved a 40-year-old female who presented with nausea, vomiting, and diarrhea after consuming wet rice noodles.
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