AI Article Synopsis
- The study evaluates the effectiveness of a new 6-minute incremental step test (6MIST) combined with portable devices as a simpler alternative to the traditional cardiopulmonary exercise test (CPET) for assessing cardiorespiratory fitness (CRF).
- Researchers enrolled 15 patients who underwent both the 6MIST and standard CPET, recording various CRF-related metrics with wearable technology during the tests.
- The results showed a strong correlation between the measurements from both tests for several CRF parameters; however, there was a weak correlation for cardiac index, indicating that while the 6MIST could be promising, it's not a complete substitute for CPET in measuring all aspects of cardiac function.
Article Abstract
Background: The cardiopulmonary exercise test (CPET) is considered a gold standard in assessing cardiorespiratory fitness (CRF) but has limited accessibility due to competency requirements and cost. Incorporating portable sensor devices into a simple bedside test of CRF could improve diagnostic and prognostic value.
Objectives: The authors sought to evaluate the association of an augmented 6-minute incremental step test (6MIST) with standard CPET.
Methods: We enrolled patients undergoing clinically indicated supine cycle ergometry CPET with invasive hemodynamics (iCPET) for the same-day 6MIST. CRF-related variables were simultaneously recorded using a signal morphology-based impedance cardiograph (PhysioFlow Enduro) and a portable metabolic analyzer (VO Master Pro) during incremental pace stationary stepping. The correlation between CPET and hemodynamic parameters from both tests was assessed using the intraclass correlation coefficient (ICC).
Results: Fifteen patients (mean age 60 ± 14 years, 40% female, 27% Black) were included. All patients who agreed to undergo 6MIST completed the study without any test-related adverse events. We observed good to excellent correlation between iCPET- and 6MIST-measured CPET parameters: peak heart rate (ICC = 0.60; 95% CI: 0.15-0.85), absolute peak O consumption (VO) (ICC = 0.77; 95% CI: 0.44-0.92), relative peak VO (ICC = 0.64; 95% CI: 0.20-0.86), maximum ventilation (ICC = 0.59; 95% CI: 0.13-0.84), O pulse (ICC = 0.71; 95% CI: 0.33-0.89), and cardiorespiratory optimal point (ICC = 0.82; 95% CI: 0.52-0.94). No significant correlation was determined between iCPET and 6MIST in measuring cardiac index at rest (ICC = 0.19; 95% CI: -0.34 to 0.63) or at peak exercise (ICC = 0.36; 95% CI: -0.17 to 0.73).
Conclusions: We demonstrate the feasibility of a novel augmented 6MIST with wearable devices for simultaneous CPET and hemodynamic assessment. 6MIST-measured CPET parameters were strongly correlated with the iCPET-derived measurements. Additional studies are needed to confirm the validity of the 6MIST compared to standard upright CPET.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11294698 | PMC |
| http://dx.doi.org/10.1016/j.jacadv.2024.101079 | DOI Listing |
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