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Advancement in the Treatment of Recurrent Pericarditis: Exploring Innovative Therapeutic Options.
S D Med
October 2024
Department of Internal Medicine, University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
Acute pericarditis, the predominant pericardial disease, often lacks a clear etiology, with 15-30% of patients experiencing recurrence, rising to 20-50% in those with prior relapses. Autoimmune mechanisms significantly contribute to recurrence, with interleukin-1 identified as a pivotal inflammatory mediator. While NSAIDs, colchicine, and steroids remain staples for acute cases, the spotlight in recurrent pericarditis management has shifted toward immunosuppressive medications.
View Article and Find Full Text PDFTwenty Years of Neuroinformatics: A Bibliometric Analysis.
Neuroinformatics
January 2025
Department of Psychology, University of Virginia, Charlottesville, VA, 22904, USA.
This study presents a thorough bibliometric analysis of Neuroinformatics over the past 20 years, offering insights into the journal's evolution at the intersection of neuroscience and computational science. Using advanced tools such as VOS viewer and methodologies like co-citation analysis, bibliographic coupling, and keyword co-occurrence, we examine trends in publication, citation patterns, and the journal's influence. Our analysis reveals enduring research themes like neuroimaging, data sharing, machine learning, and functional connectivity, which form the core of Neuroinformatics.
View Article and Find Full Text PDFScrolling to Success: Leveraging Social Media to Highlight Wellness Culture in Orthopedic Surgery Residency Programs.
Cureus
November 2024
Department of Orthopedic Surgery, Hackensack University Medical Center, Hackensack, USA.
Background Burnout, characterized by emotional exhaustion, depersonalization, and reduced personal accomplishment, profoundly affects interprofessional collaboration. Despite rising burnout rates, there is a paucity of research regarding the use of social media to support wellness culture, particularly among orthopedic surgery residents. Methods A list of all US orthopedic surgery residency programs was compiled through the Accreditation Council for Graduate Medical Education (ACGME) and associated social media accounts were identified.
View Article and Find Full Text PDFEngineering and targeting potential of CAR NK cells in colorectal cancer.
Chin Med J (Engl)
November 2024
Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, Jiangsu 225009, China.
Colorectal cancer (CRC), a major global health concern, necessitates innovative treatments. Chimeric antigen receptor (CAR) T cells have shown promise, yet they grapple with challenges. The spotlight pivots to the rising heroes: CAR natural killer (NK) cells, offering advantages such as higher safety profiles, cost-effectiveness, and efficacy against solid tumors.
View Article and Find Full Text PDFInvestigating the role of the intratumoral microbiome in thyroid cancer development and progression.
Crit Rev Oncol Hematol
December 2024
Microbiology Research Center(MRC), Pasteur Institute of Iran, Tehran, Iran; Department of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran.
The intratumoral microbiome (ITM) is in the spotlight due to its possible contribution to the initiation, progression, and invasion of a wide range of cancers. Its precise contribution to cancer tumorigenesis is still elusive, though. Thyroid cancer(TC), the ninth leading cause of cancer globally and the most prevalent endocrine malignancy with a rapidly rising incidence among all cancers, has attracted much attention nowadays.
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