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Whip It Good: A Case of Vitamin B12 Deficiency and Subacute Combined Degeneration of the Spinal Cord.
Cureus
November 2024
Neurology, Mercy Hospital Northwest Arkansas, Arkansas, USA.
A 40-year-old male patient with no significant past history presented to the emergency room with bilateral upper and lower extremity numbness and difficulty walking for three weeks. MRI of the thoracic spine revealed cord signal abnormalities in the dorsal columns consistent with selective degeneration. This was congruent with the patient's presentation and symptoms of myelopathy with dorsal column involvement along with peripheral polyneuropathy.
View Article and Find Full Text PDF[Neurological complications resulting of nitrous oxide intoxication].
Zh Nevrol Psikhiatr Im S S Korsakova
December 2024
Research Center of Neurology, Moscow, Russia.
Nitrous oxide (NO) intoxication is a common consequence of its inhalation with recreational purpose, which is prevalent among young people. The most severe result of such an entertainment is development of myelopolyneuropathy with polyneuropathy as the most common presentation, which may start acutely or subacutely. The underlying cause of neurological complications of NO intoxication is deficit of B vitamin, however its laboratory confirmation may be challenging.
View Article and Find Full Text PDFA Novel Organic-Inorganic-Nanocomposite-Based Reduced Graphene Oxide as an Efficient Nanosensor for NO Detection.
Nanomaterials (Basel)
December 2024
Faculty of Mechatronics, Informatics, and Interdisciplinary Studies, Technical University of Liberec, 46001 Liberec, Czech Republic.
There are three components to every environmental protection system: monitoring, estimation, and control. One of the main toxic gases with considerable effects on human health is NO, which is released into the atmosphere by industrial activities and the transportation network. In the present research, a NO sensor is designed based on FeO piperidine-4-sulfonic acid grafted onto a reduced graphene oxide FeO@rGO-N-(piperidine-4-SOH) nanocomposite, due to the highly efficient detection of pollution in the air.
View Article and Find Full Text PDFCombining the N Gas Flux Method and NO Isotopocule Data for the Determination of Soil Microbial NO Sources.
Rapid Commun Mass Spectrom
March 2025
School of Geography, Earth and Environmental Sciences, University of Birmingham, Birmingham, UK.
Rationale: The analysis of natural abundance isotopes in biogenic NO molecules provides valuable insights into the nature of their precursors and their role in biogeochemical cycles. However, current methodologies (for example, the isotopocule map approach) face limitations, as they only enable the estimation of combined contributions from multiple processes at once rather than discriminating individual sources. This study aimed to overcome this challenge by developing a novel methodology for the partitioning of NO sources in soil, combining natural abundance isotopes and the use of a N tracer (N Gas Flux method) in parallel incubations.
View Article and Find Full Text PDFAnesthetic management using desflurane and nitrous oxide in a child with non-ketotic hyperglycinemia: a case report.
JA Clin Rep
December 2024
Department of Anesthesiology, Niigata University Medical and Dental Hospital, 1-754 Asahimachi-Dori, Chuo-Ku, Niigata, 951-8520, Japan.
Background: Non-ketotic hyperglycinemia (NKH) is a rare autosomal recessive disorder caused by defects in the glycine cleavage system, leading to elevated glycine levels in the central nervous system. NKH manifests in various forms, with the neonatal type being the most severe and often associated with high mortality and significant neurological impairment. This case report highlights the successful uses of desflurane and nitrous oxide for anesthetic management in a patient with NKH.
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