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Cardiorespiratory dynamics in the brain: Review on the significance of cardiovascular and respiratory correlates in functional MRI signal.
Neuroimage
January 2025
Department of Radiology, Mayo Clinic, Rochester, MN, USA. Electronic address:
Article Synopsis
- Cardiorespiratory signals, previously considered noise in fMRI research, are now recognized for their potential insights into brain function and health.
- These signals, including heart rate variability and respiratory patterns, reflect the interaction between cardiovascular, respiratory, and neural systems that support brain activity.
- Understanding these signals can improve fMRI data interpretation, highlighting the connections between heart, brain, and overall physiological health.
Editorial: Methods and applications in molecular psychiatry: 2023.
Front Psychiatry
December 2024
Department of Psychiatry and Psychotherapy II, Bezirkskrankenhaus Günzburg, University of Ulm, Ulm, Germany.
Barriers impeding research data sharing on chronic disease prevention among the older adults in low-and middle-income countries: a systematic review.
Front Public Health
December 2024
School of Interdisciplinary Research and Graduate Studies, College of Graduate Studies, University of South Africa, Pretoria, South Africa.
Introduction: Chronic diseases, including cardiovascular disease, diabetes, cancer, and chronic respiratory diseases, are a growing public health concern in low-and middle-income countries (LMICs) among the older population. The current review aimed to identify the main barriers that impede researchers from sharing research data on the prevention of chronic diseases in older adults living in LMICs). The review included both older women and men from these countries.
View Article and Find Full Text PDFEvaluation of alternative vaccination routes against paratuberculosis in goats.
Front Vet Sci
November 2024
Departamento de Sanidad Animal, Instituto de Ganadería de Montaña (IGM) CSIC-ULE, León, Spain.
Paratuberculosis is a chronic granulomatous enteritis, caused by subspecies (), that affects ruminants worldwide. Vaccination has been considered the most cost-effective method for the control of this disease in infected dairy herds. However, currently available vaccines do not provide complete protection and interfere with the diagnosis of both paratuberculosis and bovine tuberculosis, limiting its use.
View Article and Find Full Text PDFCrimean-Congo hemorrhagic fever virus replicon particle vaccine is safe and elicits functional, non-neutralizing anti-nucleoprotein antibodies and T cell activation in rhesus macaques.
Antiviral Res
January 2025
Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathology, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address:
Advancement of vaccine candidates that demonstrate protective efficacy in screening studies necessitates detailed safety and immunogenicity investigations in pre-clinical models. A non-spreading Crimean-Congo hemorrhagic fever virus (CCHFV) viral replicon particle (VRP) vaccine was developed for single-dose administration to protect against disease. To date, several studies have supported safety, immunogenicity, and efficacy of the CCHF VRP in multiple highly sensitive murine models of lethal disease, but the VRP had yet to be evaluated in large animals.
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