Introduction: Tick-borne pathogens, such as spp., spp., and spp., are frequently detected in Germany. They circulate between animals and tick vectors and can cause mild to severe diseases in humans. Knowledge about distribution and prevalence of these pathogens over time is important for risk assessment of human and animal health.
Methods: nymphs were collected at different locations in 2009/2010 and 2019 in Germany and analyzed for tick-borne pathogens by real-time PCR and sequencing.
Results: spp. were detected with a prevalence of 11.96% in 2009/2010 and 13.10% in 2019 with and as dominant species. was detected in seven ticks and in coinfection with or . spp. showed a prevalence of 8.82% in 2009/2010 and 1.68% in 2019 with the exclusive detection of . The prevalence of spp. was 1.00% in 2009/2010 and 7.01% in 2019. A was detected in seven tick samples. None of the nymphs were positive for .
Discussion: Here, observed changes in prevalence were not significant after a decade but require longitudinal observations including parameters like host species and density, climatic factors to improve our understanding of tick-borne diseases.
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http://dx.doi.org/10.3389/fcimb.2024.1429667 | DOI Listing |
Sci Rep
January 2025
Vibrant Sciences LLC., San Carlos, CA, USA.
Tick-borne infections are the most common vector-borne diseases in the USA. Ticks harbor and transmit several infections with Lyme disease being the most common tickborne infection in the US and Europe. Lack of awareness about tick populations, specific diagnostic tests, and overlapping signs and symptoms of tick-borne infections can often lead to misdiagnosis affecting treatment and the prevalence data reported especially for non-Lyme tick-borne infections.
View Article and Find Full Text PDFUnlabelled: How tick-borne pathogens interact with their hosts has been primarily studied in vertebrates where disease is observed. Comparatively less is known about pathogen interactions within the tick. Here, we report that ticks infected with either (causative agent of anaplasmosis) or (causative agent of Lyme disease) show activation of the ATF6 branch of the unfolded protein response (UPR).
View Article and Find Full Text PDFVet World
November 2024
Department of Microbiology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Background And Aim: Tick-borne pathogens pose a significant problem in canines, other animals, and humans worldwide. This study aimed to estimate the prevalence of , and in dogs and associated ticks in Egypt.
Materials And Methods: Blood samples from 110 tick-infested dogs and 550 whole ticks (divided into 110 pools) were collected and tested for the targeted pathogens using polymerase chain reaction (PCR).
Virology
January 2025
Transboundary Animal Diseases Research Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan. Electronic address:
Oz virus (OZV), a tick-borne, six-segmented negative-strand RNA virus in the genus Thogotovirus, caused a fatal human infection in Japan in 2023. To study viral RNA synthesis, we developed an OZV minigenome assay using mammalian cells. This revealed variations in promoter activities among the six genome segments.
View Article and Find Full Text PDFTicks Tick Borne Dis
January 2025
Department of Microbiology and Immunology, Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:
Ticks are an increasingly important threat to public health in Southeast Asia, due to the role of many tick species as parasites of humans and as vectors of zoonotic pathogens. Singapore is a densely populated Southeast Asian nation with a rich tick fauna and a significant mosaic of city and greenspace. However, apart from occasional case reports, the human-biting ticks in Singapore have received little attention from researchers.
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