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The Creation of Intensional Medication Lists Using the NHS Dictionary of Medicines and Devices.
Stud Health Technol Inform
November 2024
Nuffield Department of Primary Care Health Sciences, University of Oxford, UK.
The identification of medications prescribed to patients in routinely collected health records is an important part of the identification of cohorts for surveillance and research. Preparations available for prescription can change frequently and this presents challenges to the maintenance of extensional or "flat lists" of medications, particularly in ongoing studies such as disease surveillance. The NHS publishes a Dictionary of Medicines and Devices weekly, listing almost all the medications available in the UK as an extension to the UK edition of SNOMED CT.
View Article and Find Full Text PDFThe British Missionaries' Attempts to Identify Chinese Medicine.
Ber Wiss
December 2024
Institute of Modern History, Academia Sinica.
The Western world has a profound historical engagement with medicinal resources originating from China. Following the Opium War, missionaries were granted access to China and established residence there. Motivated by clinical necessities and the inquisitiveness of the Western scientific community, these missionaries meticulously documented the medicinal resources available in China, endeavoring to incorporate this knowledge into Western pharmacology.
View Article and Find Full Text PDFDevelopment of a text mining algorithm for identifying adverse drug reactions in electronic health records.
JAMIA Open
October 2024
Department of Clinical Pharmacy, University Medical Centre Utrecht, 3584 CX Utrecht, The Netherlands.
Objective: Adverse drug reactions (ADRs) are a significant healthcare concern. They are often documented as free text in electronic health records (EHRs), making them challenging to use in clinical decision support systems (CDSS). The study aimed to develop a text mining algorithm to identify ADRs in free text of Dutch EHRs.
View Article and Find Full Text PDFMetabolic dysfunction-associated steatotic liver disease: Evolution of the final terminology.
Eur J Intern Med
June 2024
Division of Gastroenterology, Hepatology and Endoscopy, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA; Section of Gastroenterology, Department of Medicine, VA Boston Healthcare System, Boston, MA, USA.
The medical term nonalcoholic fatty liver disease (NAFLD) was coined in 1986 for a condition that has since become the most prevalent liver disorder worldwide. In the last 3 years, the global professional community launched 2 consecutive efforts to purge NAFLD from the medical dictionary and recommended new terms based on disease pathophysiology rather than distinction from similar conditions featuring liver steatosis. A consensus by renowned clinical scholars primarily residing in the Asian-Pacific region introduced metabolic dysfunction-associated fatty liver disease (MAFLD) as a new name to replace NAFLD in 2020.
View Article and Find Full Text PDFGuided construction of single cell reference for human and mouse lung.
Nat Commun
July 2023
The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.
Accurate cell type identification is a key and rate-limiting step in single-cell data analysis. Single-cell references with comprehensive cell types, reproducible and functionally validated cell identities, and common nomenclatures are much needed by the research community for automated cell type annotation, data integration, and data sharing. Here, we develop a computational pipeline utilizing the LungMAP CellCards as a dictionary to consolidate single-cell transcriptomic datasets of 104 human lungs and 17 mouse lung samples to construct LungMAP single-cell reference (CellRef) for both normal human and mouse lungs.
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