Metabolic Profile in Rats during Long-Term Restriction of Motor Activity.

Bull Exp Biol Med

Kirov State Medical University, Ministry of Health of the Russian Federation, Kirov, Russia.

Published: June 2024

We performed a comprehensive study of protein (total protein, medium-molecular-weight peptides, creatinine, and urea), purine (uric acid), and lipid (cholesterol, triglycerides) metabolism, activity of AST, ALT, and acid phosphatase in blood plasma of white male rats under conditions of restriction of motor activity up to 28 days. Patterns of changes in metabolic profile during hypokinesia were established: prevalence of catabolic processes and atherogenic shifts in the lipid spectrum with maximum manifestation on 14-21 days of the experiment.

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http://dx.doi.org/10.1007/s10517-024-06152-6DOI Listing

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