A preparation of interferon-alpha 2C of high purity formed by recombinant DNA technology was used as adjuvant therapy following removal of laryngeal papillomas by cauterization or laser vaporization. Preliminary data on 20 patients are reported and include 11 complete and 7 partial responses. Side-effects included initial temperature elevation, but this subsided and other side-effects were uncommon. No antibodies to the interferon preparation were found in any of the patients.

Download full-text PDF

Source
http://dx.doi.org/10.1159/000226079DOI Listing

Publication Analysis

Top Keywords

recombinant interferon-alpha-2c
4
interferon-alpha-2c laryngeal
4
laryngeal papillomatosis
4
papillomatosis preliminary
4
preliminary prospective
4
prospective multicentre
4
multicentre trial
4
trial preparation
4
preparation interferon-alpha
4
interferon-alpha high
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!