From the University Grenoble Alpes, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, CHU Grenoble Alpes, TIMC, UMR5525 (CS-I, PB, PA, JP), Department of Pharmacy, University Grenoble Alpes (CS-I, CP, PB) and Department of Anesthesia and Critical Care, CHU Grenoble Alpes, Grenoble, France (PA, JP).