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A novel skin-like patch based on 3D hydrogel nanocomposite of Polydopamine/TiO nanoparticles and Ag quantum dots accelerates diabetic wound healing compared to stem cell therapy.
J Tissue Viability
December 2024
Institute of Nanoscience & Nanotechnology, Kafrelsheikh University, Kafr ElSheikh, 33516, Egypt; Nile Valley University, Fayoum, 63518 Egypt. Electronic address:
Despite the advances in the development of therapeutic wearable wound-healing patches, lack self-healing properties and strong adhesion to diabetic skin, hindering their effectiveness. We propose a unique, wearable patch made from a 3D organo-hydrogel nanocomposite containing polydopamine, titanium dioxide nanoparticles, and silver quantum dots (PDA-TiO@Ag). The designed patch exhibits ultra-stretchable, exceptional-self-healing, self-adhesive, ensuring conformal contact with the skin even during movement.
View Article and Find Full Text PDFThermoelectric Gel Enabling Self-Powered Facial Perception for Expression Recognition and Health Monitoring.
ACS Sens
December 2024
College of Integrated Circuits, Taiyuan University of Technology, Taiyuan 030024, China.
By analyzing facial features to perform expression recognition and health monitoring, facial perception plays a pivotal role in noninvasive, real-time disease diagnosis and prevention. Current perception routes are limited by structural complexity and the necessity of a power supply, making timely and accurate monitoring difficult. Herein, a self-powered poly(vinyl alcohol)-gellan gum-glycerol thermogalvanic gel patch enabling facial perception is developed for monitoring emotions and atypical pathological states.
View Article and Find Full Text PDFAdvanced Wearable Devices for Monitoring Sweat Biochemical Markers in Athletic Performance: A Comprehensive Review.
Biosensors (Basel)
November 2024
Department of Experimental Medicine, University of Salento, 73100 Lecce, Italy.
Wearable technology has advanced significantly, offering real-time monitoring of athletes' physiological parameters and optimizing training and recovery strategies. Recent developments focus on biosensor devices capable of monitoring biochemical parameters in addition to physiological ones. These devices employ noninvasive methods such as sweat analysis, which reveals critical biomarkers like glucose, lactate, electrolytes, pH, and cortisol.
View Article and Find Full Text PDFDeveloping a Sleep Algxorithm to Support a Digital Medicine System: Noninterventional, Observational Sleep Study.
JMIR Ment Health
December 2024
Otsuka Pharmaceutical Development & Commercialization, Inc, 508 Carnegie Center Drive, Princeton, NJ, 08540, United States, 1 609 535 9035.
Background: Sleep-wake patterns are important behavioral biomarkers for patients with serious mental illness (SMI), providing insight into their well-being. The gold standard for monitoring sleep is polysomnography (PSG), which requires a sleep lab facility; however, advances in wearable sensor technology allow for real-world sleep-wake monitoring.
Objective: The goal of this study was to develop a PSG-validated sleep algorithm using accelerometer (ACC) and electrocardiogram (ECG) data from a wearable patch to accurately quantify sleep in a real-world setting.
Integrated Wearable Flexible Hydrogel Patch Sensing System for the Detection of Physiological Markers.
Anal Chem
December 2024
School of Agricultural Engineering, Jiangsu University, Zhenjiang 212013, PR China.
Conventional wearable flexible sensing systems typically comprise three components: a flexible substrate that contacts the skin, a signal processing module, and a signal output module. These components function relatively independently, resulting in a complex system that lacks sufficient integration. Therefore, developing an integrated wearable flexible sensing system by combining the flexible substrate, the signal processing module, and the signal output module not only enhances performance and comfort, but also reduces manufacturing costs and the risk of failure.
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