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Patient-Centered Discharge and Postoperative Length of Hospital Stay in Primary Total Knee Arthroplasty.
Cureus
December 2024
Division of Information Science and Biostatistics, Niigata University Hospital, Niigata, JPN.
Background This study aimed to identify factors affecting the length of hospital stay (LOS) after total knee arthroplasty (TKA) in patients classified as American Society of Anesthesiologists (ASA) physical status I or II, with a focus on patient-dependent determination of discharge. The goal was to explore strategies to shorten LOS. Methods A retrospective cohort study was conducted on 398 patients (494 knees) who underwent primary TKA.
View Article and Find Full Text PDFNovel indicator of microvascular complications in patients with type 2 diabetes mellitus and shortened erythrocyte lifespan: a multicenter cross-sectional analysis.
Diabetol Metab Syndr
January 2025
NHC Key Lab of Hormones and Development and Tianjin Key Lab of Metabolic Diseases, Tianjin Medical University Chu Hsien-I Memorial Hospital & Institute of Endocrinology, Tianjin, 300134, China.
Introduction: In this study, we assessed whether the ratio of glucose management index (GMI) to glycated albumin (GA) was linked to microvascular complications in patients with type 2 diabetes mellitus (T2DM) who also possessed a shortened erythrocyte lifespan.
Methods: This study encompassed individuals from the Tianjin Diabetic Retinopathy Screening Cohort who completed continuous glucose monitoring and had an erythrocyte lifespan of under 90 days. Differences in GMI/GA were compared between the T2DM patients with or without microvascular complications, including diabetic kidney disease (DKD) and diabetic retinopathy (DR).
Rational use of human albumin: plan-do-check-act cycle in clinical practice.
BMJ Support Palliat Care
January 2025
Department of Pharmacy, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, Fujian, China
Objective: Improper use of human albumin (HA) is now common in clinical settings. This study aims to explore the feasibility of the plan-do-check-act (PDCA) cycle in promoting the rational use of HA.
Methods: The differences between the control and observation groups (after the PDCA cycle) in terms of serum albumin detection rate, serum albumin values, HA usage, and rationality were analysed and compared using a before-and-after control method.
Percutaneous cholecystostomy in elderly patients with acute cholecystitis: Factors influencing mortality, morbidity, and length of hospital stay.
Ulus Travma Acil Cerrahi Derg
January 2025
Interventional Radiology Department, University of Health Sciences, Istanbul Training and Research Hospital, Istanbul-Türkiye.
Background: Acute cholecystitis (AC) is increasingly common and imposes a burden on healthcare systems, particularly in the elderly population. While laparoscopic cholecystectomy (LC) is the definitive treatment, percutaneous cholecystostomy (PC) is often preferred based on various factors. The treatment of elderly patients requires a multidisciplinary approach that carefully assesses surgical risks due to age-related changes and comorbidities.
View Article and Find Full Text PDFUnlocking the Antibacterial Potential of Naphthalimide-Coumarins to Overcome Drug Resistance with Antibiofilm and Membrane Disruption Ability against .
ACS Appl Mater Interfaces
January 2025
Department of Chemistry and Biochemistry, Thapar Institute of Engineering and Technology, Patiala 147004, Punjab, India.
Resistance by bacteria to available antibiotics is a threat to human health, which demands the development of new antibacterial agents. Considering the prevailing conditions, we have developed a library of new naphthalimide-coumarin moieties as broad-spectrum antibacterial agents to fight against awful drug resistance. Preliminary studies indicate that compounds and display excellent antibacterial activity against , exceeding the performance of marketed drug amoxicillin.
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