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Erythematous Flaky Rash on the Toe.
Cutis
June 2024
Sarah K. Friske is from the School of Medicine, Baylor College of Medicine, Houston, Texas. Drs. Wiggins, Carrigg, and Bohlke are from Good Samaritan Health Services/Frontier Derm, Salem, Oregon. Dr. Seervai is from Oregon Health & Science University, Portland.
Attenuated effects of topical vinpocetine in an imiquimod-induced mouse model of psoriasis.
J Taibah Univ Med Sci
February 2024
University of Al-Qadisiyah, College of Pharmacy, Department of Pharmaceutics, Al Diwaniya, Al-Qadisiyah Province, Iraq.
Unlabelled: Psoriasis is an uncontrolled, long-lasting inflammatory dermatosis distinguished by thickened, erythematous, and flaky skin lesions. Massive amounts of inflammatory cytokines are produced when immune system imbalances are driven by genetic and environmental triggers. Vinpocetine (VNP), a man-made analogue of the compound vincamine found in the dwarf periwinkle herb, has robust anti-inflammatory, immunomodulatory, and anti-oxidative effects; alleviates the epidermal penetration of immune cells, such as eosinophils and neutrophils; and abolishes the generation of pro-inflammatory molecules.
View Article and Find Full Text PDFScaly erythematous eruptions of intertriginous locations.
N Z Med J
July 2023
Dermatologist, FACD, Queensland Institute of Dermatology, South Brisbane, Queensland, Australia.
Article Synopsis
- - Intertriginous or flexural eruptions are common skin issues that often lead to different potential diagnoses in clinical practice.
- - The study discusses a case of a female with flaky red eruptions, ultimately diagnosed as granular parakeratosis, affecting both nonflexural (mid-back) and flexural areas (groin, gluteal fold, etc.).
- - The condition was managed effectively with strong topical steroids and by avoiding triggers, leading to resolution of symptoms within 4 weeks.
Dyshidrotic eczema and seborrheic dermatitis-like eczematous eruption following intravenous immunoglobulin therapy.
Dermatol Ther
November 2020
Department of Dermatology, Medical Faculty, Istanbul Medeniyet University, Göztepe Research and Training Hospital, Istanbul, Turkey.
Intravenous immunoglobulin (IVIg) is increasingly used for the treatment of inflammatory and autoimmune diseases. Although skin reactions to IVIg therapy are usually minor, rare, and not life-threatening, dermatologists need to recognize the nature of these adverse reactions. We describe a 33-year-old man suffering from demyelinating polyneuropathy who developed dyshidrotic eczema on the palms and flaky grayish-white scales on an erythematous base on his face after the administration of IVIg.
View Article and Find Full Text PDFHand-foot syndrome due to hepatitis C therapy.
Rev Assoc Med Bras (1992)
May 2018
Department of Gastroenterology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, SP, Brasil.
Introduction: Direct-acting antivirals are new drugs for chronic hepatitis C treatment. They are usually safe and well tolerated, but can sometimes cause serious adverse effects and there is no consensus on how to treat or prevent them. We described a case of hand-foot syndrome due to hepatitis C virus interferon-free therapy.
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