Objectives: to analyze the trends and factors associated with family refusal of skin donation for transplantation.
Methods: this cross-sectional study was conducted in the State of São Paulo, with family authorization terms collected from 2001 to 2020. The variables analyzed included year, age, gender, cause of death, and type of institution. Data were analyzed using linear and multiple logistic regression, with the Odds Ratio estimated at p<0.05 for statistical significance.
Results: 1,355 individuals refused skin donation. The trend of refusals decreased between 2001 and 2009 in the age groups of 0-11 years and 12-19 years, but increased in the group aged ≥60 years. This trend continued to decrease in the 0-11 years group from 2010 to 2020, and increased in the 20-40 years group. Males and the age groups of 20-40 years, 41-59 years, and ≥60 years exhibited 27%, 34%, 47%, and 53% lower chances of refusal, respectively.
Conclusions: there is an urgent need for measures to mitigate the high number of refusals associated with skin donation.
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http://dx.doi.org/10.1590/0034-7167-2023-0209 | DOI Listing |
Pharmacy (Basel)
January 2025
iMed.ULisboa-Research Institute for Medicines, Faculty of Pharmacy, University of Lisbon, 1649-003 Lisboa, Portugal.
Multimorbidity and polypharmacy are prevalent among Long-Term Care (LTC) users. Older people, who most use LTC services, are more prone to drug-related problems, which polypharmacy aggravates. Deprescribing is a key intervention to address polypharmacy and inappropriate medication.
View Article and Find Full Text PDFPediatr Transplant
February 2025
School of Nursing, University of São Paulo, São Paulo, Brazil.
Background: When a family decides to donate the organs or tissues of their child with brain death, it is necessary to consider which organs or tissues will be donated. This phenomenon presents an ethical dilemma that is underexplored in the scientific literature, making it essential to examine this context to understand how refusals occur within donations.
Objective: To analyze the rates and trends of specific refusals for each organ and tissue from pediatric donors with brain death occurring between 2001 and 2020 in an Organ Procurement Organization in the State of São Paulo, Brazil.
BMC Public Health
January 2025
School of Health and Allied Sciences, Pokhara University, Kaski, Nepal.
Background: Minimum acceptable diet (MAD) intake is crucial for optimizing the growth and development of children aged 6 to 23 months. However, little is known about the factors influencing MAD intake among children of Sudurpaschim. This study, therefore, aims to assess the prevalence of minimum acceptable diet intake and associated factors among children aged 6-23 months in Sudurpaschim Province of Nepal.
View Article and Find Full Text PDFKlin Padiatr
January 2025
Allergy and Clinical Immunology, University Children's Hospital Basel, Basel, BS, CH, Basel, Switzerland.
Evaluation of the cow's milk (CM) and hen's egg (HE) ladder to improve medical care of children with CM and/or HE allergy. Through an anonymous retrospective online questionnaire, we investigated parent perspectives regarding the therapy option of a CM and HE ladder in children with CM and/or HE allergy. Of the 54 families contacted, 29 took part in the study.
View Article and Find Full Text PDFJ Allergy Clin Immunol Pract
January 2025
University of Queensland, St Lucia, Australia; Centre for Food Allergy Research, Murdoch Children's Research Institute, Parkville, Australia. Electronic address:
Background: Following a negative oral food challenge (OFC), it is recommended the individual continues to consume the historical allergen regularly. However, the proportion of families achieving sustained reintroduction, and enablers and barriers for reintroduction, are currently unclear.
Objective: To understand the frequency and definitions of optimal food reintroduction in children and adolescents following negative OFC, and associated barriers and enablers.
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