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Psoriasis increases the risk of Sjögren's syndrome: evidence from a propensity score-matched cohort study and transcriptomic analysis.
BMC Med
January 2025
Department of Rheumatology and Immunology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Despite the well-documented immune dysregulation in both psoriasis and Sjögren's syndrome (SS), the specific link between these two autoimmune diseases has not been extensively explored. The present study aims to investigate the impact of psoriasis on the risk of SS.
Methods: A retrospective cohort study using TriNetX data compared SS development in patients with psoriasis and controls using propensity score matching, Kaplan-Meier curves, and Cox models.
Oxidative stress and retinopathy: evidence from epidemiological studies.
J Transl Med
January 2025
Cancer Center, The First Hospital of Jilin University, No.1 Xinmin Street, Changchun, China.
Background: Previous studies have suggested oxidative stress may play a key role in the pathogenesis of retinopathy, while evidence from observational studies directly linking oxidative biomarkers to clinically relevant outcomes has been limited. This study aims to investigate the association between oxidative balance score (OBS) and prevalence of retinopathy in a nationally representative sample of U.S.
View Article and Find Full Text PDFNeuroeconomically dissociable forms of mental accounting are altered in a mouse model of diabetes.
Commun Biol
January 2025
Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Those with diabetes mellitus are at high-risk of developing psychiatric disorders, especially mood disorders, yet the link between hyperglycemia and altered motivation has not been thoroughly explored. Here, we characterized value-based decision-making behavior of a streptozocin-induced diabetic mouse model on Restaurant Row, a naturalistic neuroeconomic foraging paradigm capable of behaviorally capturing multiple decision systems known to depend on dissociable neural circuits. Mice made self-paced choices on a daily limited time-budget, accepting or rejecting reward offers based on cost (delays cued by tone pitch) and subjective value (flavors), in a closed-economy system tested across months.
View Article and Find Full Text PDFInsights from a century of data reveal global trends in ex situ living plant collections.
Nat Ecol Evol
January 2025
Cambridge University Botanic Garden, Cambridge, UK.
Ex situ living plant collections play a crucial role in providing nature-based solutions to twenty-first century global challenges. However, the complex dynamics of these artificial ecosystems are poorly quantified and understood, affecting biodiversity storage, conservation and utilization. To evaluate the management of ex situ plant diversity, we analysed a century of data comprising 2.
View Article and Find Full Text PDFThe curvilinear relationship between hepatic steatosis index and depression: Findings from the NHANES.
J Affect Disord
January 2025
Affiliated Hospital of Shandong University of Traditional Chinese Medicine, No. 16369, Jingshi Road, Jinan City, Shandong Province, China; Shandong University of Traditional Chinese Medicine, No. 16369, Jingshi Road, Jinan City, Shandong Province, China. Electronic address:
Background: Previous studies have established a link between depression and fatty liver disease, yet the relationship with the Hepatic Steatosis Index (HSI) has not been thoroughly investigated. This study aims to explore the potential association between HSI and depression.
Methods: We investigated the association between HSI and depression (PHQ-9 depression score ≥ 10) using a weighted multiple logistic regression model and stratified analysis.
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