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Adverse outcomes in monochorionic twins with amniotic fluid abnormalities without TTTS: A Case-Control study.
Eur J Obstet Gynecol Reprod Biol
January 2025
Baylor College of Medicine Houston TX, United States.
Objective: Monochorionic diamniotic (MCDA) twins with amniotic fluid abnormalities that do not meet criteria for twin-twin transfusion syndrome (TTTS) concern physicians and families. This study aimed to describe the natural history of amniotic fluid abnormalities.
Methods: In this retrospective case-control study, TTTS screening ultrasounds and clinical records throughout all MCDA twin gestations were reviewed between 2018 and 2022 at a tertiary fetal care center.
Inaccuracy of Temporal Thermometer Measurement by Age and Race.
Acad Pediatr
December 2024
Department of Emergency Medicine (RA Salhi, MA Meeker, and ME Samuels-Kalow), Massachusetts General Hospital, Boston, Mass.
Objective: Rapid vital sign assessment, including temperature measurement, is critical among pediatric patients presenting to the emergency department (ED). While error rates in temporal thermometry are well documented, the potential for differential error rates by demographics is not well established. Our objective was to evaluate error rates of temporal thermometers by demographic variables, specifically race and age, among pediatric patients in the ED.
View Article and Find Full Text PDFAssociation of polygenic liabilities for schizophrenia and bipolar disorder with educational attainment and cognitive aging.
Transl Psychiatry
November 2024
National Center for Geriatrics and Welfare Research, National Health Research Institutes, Zhunan, Taiwan.
Article Synopsis
- This study investigated the genetic links between schizophrenia (SCZ) and bipolar disorder (BPD), focusing on how polygenic risks for these disorders relate to education and cognitive aging.
- Analyzing data from over 106,000 participants, researchers found that certain genetic scores positively correlated with educational achievement, while others had a negative impact.
- The findings indicate that SCZ and BPD have different genetic influences, affecting educational success and cognitive decline, suggesting that these disorders are not genetically the same.
Discordant definitions of small airway dysfunction between spirometry and parametric response mapping: the HRCT-based study.
Insights Imaging
October 2024
Department of Radiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Article Synopsis
- The study aimed to explore lung structure differences in small airway dysfunction (SAD) using both spirometry and parametric response mapping (PRM) evaluated through high-resolution computed tomography (HRCT).
- It involved 388 participants who underwent pulmonary function tests and chest CT scans, leading to the identification of predictive factors for SAD based on clinical and imaging data.
- Results indicated that spirometry-defined SAD was more related to airway morphology, while PRM was more sensitive to early dysfunction, and predictive models combining clinical data and HRCT assessments showed high accuracy.
Ex Ovo Chorioallantoic Membrane Assay as a Model of Bone Formation by Biomaterials.
ACS Macro Lett
October 2024
Regenerative Biomaterials Research Group, The RAFT Institute and The Griffin Institute, Northwick Park and Saint Mark's Hospitals, Harrow HA1 3UJ, United Kingdom.
Article Synopsis
- - Biomaterials, essential for bone tissue engineering, require careful selection and assessment for effective clinical use, as existing models often face challenges like high costs and ethical concerns.
- - Researchers proposed using the chick embryo chorioallantoic membrane as a model to test initial bone formation with scaffolds, specifically a fibrin-alginate-calcium phosphate (FACaP) material.
- - Initial results showed early signs of bone formation and blood vessel infiltration in the scaffolds, making FACaP a promising biomaterial for applications where heavy load-bearing isn't necessary.
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