Prolonged treatment of neuroendocrine carcinoma of the cervix with a PARP inhibitor based on next generation sequencing.

Gynecol Oncol Rep

Women's Health Institute, Cleveland Clinic Foundation, A-81, 9500 Euclid Ave., Cleveland, OH 44195, United States.

Published: August 2024

•Next generation sequencing identified a BRCA 2 mutation in a patient with stage IVB neuroendocrine cancer of the cervix.•Treatment with rucaparib resulted in disease stabilization for 74 months.•The patient remains fully active working full time as a nurse and pursing a nurse practitioner degree.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11287010PMC
http://dx.doi.org/10.1016/j.gore.2024.101458DOI Listing

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