Correlation between viral infections in male semen and infertility: a literature review.

Virol J

Department of Reproductive Medicine, NHC Key Laboratory of Healthy Birth and Birth Defect Prevention in Western China, the First People's Hospital of Yunnan Province, Kunming, Yunnan, China.

Published: July 2024

AI Article Synopsis

  • Infertility impacts about one-sixth of couples worldwide, with male infertility rates on the rise.
  • This review highlights 40 viruses found in human semen, detailing their characteristics, transmission modes, and effects on reproductive and endocrine health.
  • It also discusses pathogenic mechanisms and treatment options for viruses linked to male infertility, aiming to improve understanding and inform future research and treatment strategies.

Article Abstract

Infertility affects approximately one-sixth of couples globally, with the incidence of male infertility steadily increasing. However, our understanding of the impact of viral infections on fertility remains limited. This review consolidates findings from previous studies, outlining 40 viruses identified in human semen and summarizing their key characteristics, modes of transmission, and their effects on both the reproductive and endocrine systems. Furthermore, it elucidates potential pathogenic mechanisms and treatment prospects of viruses strongly associated with male infertility. This synthesis will enhance our comprehension of how viral infections influence male reproductive health, offering valuable insights for future research as well as the diagnosis and treatment of infectious infertility.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11290048PMC
http://dx.doi.org/10.1186/s12985-024-02431-wDOI Listing

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