Airborne microorganisms pose a significant health threat, causing various illnesses. Traditional detection methods are often slow and complex. This review highlights the potential of nanomaterial-based biosensors, particularly colorimetric sensors, for rapid and on-site detection of airborne microbes. Colorimetric sensors offer real-time visual detection without complex instrumentation. We explore the integration of these sensors with Lab-on-a-Chip technology using PDMS microfluidics. This review also proposes a novel PDMS-based colorimetric biosensor for real-time detection of airborne microbes. The sensor utilizes a color change phenomenon easily observable with the naked eye, simplifying analysis and potentially enabling point-of-care applications.
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http://dx.doi.org/10.1186/s11671-024-04065-x | DOI Listing |
Sensors (Basel)
January 2025
Jiangsu Key Laboratory of TCM Evaluation and Translational Research, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, China.
Flavokavain B (FKB), a hepatotoxic chalcone from (kava), has raised safety concerns due to its role in disrupting redox homeostasis and inducing apoptosis in hepatocytes. Conventional chromatographic methods for FKB detection, while sensitive, are costly and impractical for field applications. In this work, DNA aptamers were selected using the library-immobilized method and high-throughput sequencing.
View Article and Find Full Text PDFMolecules
January 2025
Department of Chemistry and Biochemistry, University of Colorado, Colorado Springs, CO 80918, USA.
Catalytically active nanomaterials, or nanozymes, have gained significant attention as alternatives to natural enzymes due to their low cost, ease of preparation, and enhanced stability. Because of easy preparation, excellent biocompatibility, and unique optoelectronic properties, gold nanoparticles (AuNPs) have attracted increasing attention in many fields, including nanozymes. In this work, we demonstrated the applicability of beta-cyclodextrin functionalized gold nanoparticles (β-CD-AuNPs) as enzyme mimics for different substances, including TMB and DA.
View Article and Find Full Text PDFInt J Pharm
January 2025
Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM'S NMIMS, V. L. Mehta Road, Vile Parle (W), Mumbai, India. Electronic address:
Diabetes is a disorder attributed to impaired production or utilization of insulin and requires rapid precise monitoring of glucose levels. The fabrication of nanotechnology-based non-invasive biosensors for glucose detection holds significant promise for improved diabetes care and point-of-care diagnostics. The study demonstrates a novel molecularly imprinted polymers (ADMIPs) based sensitive biosensor for glucose estimation in saliva using three distinct sensing platforms -cotton swab, paper strip and polymeric film by colorimetric assay.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
January 2025
Laboratory of Organic Chemistry, Tarsadia Institute of Chemical Science, Uka Tarsadia University, Maliba Campus, Gopal Vidyanagar, Bardoli-Mahuva Road, Tarsadi 394650 Surat Gujarat India. Electronic address:
A single molecule sensor for several analytes is indeed desired by the scientists around the world due to obvious advantages. In this report we present a new class of Lophine incorporated azo dyes that has capacity of differential colorimetric detection of several metal ions. Interestingly the sensor was found to have pH dependent selective response towards several metals.
View Article and Find Full Text PDFNanomaterials (Basel)
January 2025
Department of Physics and Engineering, Moldova State University, MD-2009 Chisinau, Moldova.
This article analyzes the prospects for the appearance of paper-based sensors on the sensor market. It is concluded that paper-based sensors are not a fantasy but a reality. It is shown that paper has properties that make it possible to develop a wide variety of paper-based sensors, such as SERS, colorimetric, fluorescent, conductometric, capacitive, fiber-optic, electrochemical, microfluidic, shape-deformation, microwave, and various physical sensors.
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