AI Article Synopsis

  • - This study looked at how the shape of the reconstructed portal vein/superior mesenteric vein (PV/SMV) affects long-term nutrition after pancreatic surgery (pancreatoduodenectomy) using a technique called computational fluid dynamics (CFD).
  • - Twenty-four patients who had the surgery and were tumor-free for over 9 months were analyzed by creating 3D models from their CT scans taken 3-6 months post-surgery.
  • - Results showed that patients with higher pressure or turbulence in blood flow were more likely to experience poorer nutritional recovery within 9 months, demonstrating that CFD can help assess the effectiveness of vein reconstructions.

Article Abstract

This study evaluated the impact of reconstructed portal vein/superior mesenteric vein (PV/SMV) morphology on the long-term nutritional status following pancreatoduodenectomy (PD) using computational fluid dynamics (CFD). Twenty-four patients who underwent PD with PV/SMV resection and reconstruction without tumor recurrence for over 9 months after the operation were enrolled in the study. Three-dimensional models were constructed from computed tomography images obtained 3-6 months postoperatively. The pressure (p) at the inlet and turbulence dissipation rate (ε) at the outlet were investigated in the models. Patients with values of either p or ε above the upper interquartile range were classified as the poor flow group. The prognostic nutritional index improvement rate was significantly lower at 9 postoperative months in the poor flow group than in the good flow group (P = 0.016). This finding indicates the utility of a CFD analysis for evaluating the reconstructed PV/SMV morphology.

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Source
http://dx.doi.org/10.1007/s00595-024-02903-0DOI Listing

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