The forehead is the cranial part of the forehead, and represents an important component of facial esthetics. The deformations linked to craniosynostoses are characterized by modifications in height, width, and angulation. Their surgical correction during childhood is based on well-established techniques of remodeling using resorbable osteosynthesis. Today, distraction and springs allow less invasive procedures with good outcomes. Sequellae mainly correspond to hypotrophies of the temporal region, corrected with fat grafting. The presence of a mutation increases the risk of reoperation in the first six years of life.
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Detection of inversion with breakpoints in causing MPS VI by whole-genome sequencing: lessons learned and best practices.
Front Genet
January 2025
Genetics and Precision Medical Center, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Introduction: Mucopolysaccharidosis type VI (MPSVI), an autosomal recessive lysosomal storage disorder caused by pathogenic variants in gene. Usually, whole exome sequencing (WES) can identify these variants, and if WES failed to detect causative variants, whole-genome sequencing (WGS) may be considered to investigate deep intronic variations and structural alterations in patients.
Methods: Whole-exome sequencing (WES) and whole genome sequencing (WGS) were performed in a Chinese family having a boy with suspected diagnosis of MPS with macrocephaly, coarse facial features, broad forehead, thick lips, frontal bossing, craniosynostosis, blue spots, frequent upper respiratory infections, inguinal hernia, and dysostosis multiplex.
Exploring Visual Outcomes in Late-Presenting Multisuture Craniosynostosis: A Case Report.
Cureus
December 2024
Neuro Ophthalmology, Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Puducherry, IND.
A five-year-old female came with a history of frequent rubbing of the right eye and noticed prolonged elevation of her head since birth, informed by her mother. On ocular examination, the best corrected visual acuity shown in the right eye was 1/60, and the left eye was 6/6, with proptosis in both eyes. Fundus examination showed both eyes having pale discs.
View Article and Find Full Text PDFPhotogrammetric evaluation of extended midline strip craniectomy with bilateral parietal osteotomies on frontal morphology in patients with isolated sagittal synostosis.
Neurosurg Focus
January 2025
Departments of1Cranio- and Maxillofacial Surgery and.
Article Synopsis
- The study investigates the effectiveness of a surgical procedure (extended strip craniectomy with bilateral barrel staving) for treating isolated craniosynostosis of the sagittal suture in infants, specifically focusing on its impact on cranial shape without directly addressing forehead issues.
- Results showed significant improvements in aspects like bossing angle and cephalic index over a year, although the cranial shape did not entirely match that of healthy peers, indicating partial normalization but not complete correction.
- The research validates 3D photogrammetry as a useful noninvasive tool for assessing cranial changes post-surgery, suggesting potential for wider clinical applications in monitoring cranial morphology.
[Development and growth of the forehead].
Ann Chir Plast Esthet
November 2024
Laboratoire Forme et croissance du crâne, Institut Imagine, Paris, France; Service de chirurgie maxillofaciale et chirurgie plastique, Hôpital Necker-Enfants malades, AP-HP, Paris, France; CRMR CRANIOST, Filière TeteCou ; ERN CRANIO; Faculté de médecine, Université Paris-Cité, Paris, France. Electronic address:
Craniofacial development involves processes leading to the positioning and early growth of the frontal ossification centers. Growth then occurs, mostly secondary to the activity of the sutures, with major interactions with the functional environment, mostly consisting in the growing brain, based on mechanosensation and mechanotransduction mechanisms. Here, we review these processes and assess their relevance in the understanding of craniofacial malformations.
View Article and Find Full Text PDFStaged dissection reduces blood loss in surgery for metopic synostosis.
J Plast Surg Hand Surg
November 2024
Department of Plastic Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Plastic Surgery, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.
Introduction: Fronto-orbital remodelling for metopic synostosis is an extensive operation with substantial blood loss, particularly from emissary veins in the glabellar region. One possibility to reduce blood loss may be to stage dissection and cauterise anomalous emissary veins before dissecting in the subperiostal plane. OBJECTIVE: The aim of the present study was to compare perioperative bleeding using a staged dissection in the glabellar region with the traditional subperiostal dissection technique during surgery for metopic synostosis.
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