'Living drugs' target CD70 in advanced renal tumors.

Trends Pharmacol Sci

Department of Internal Medicine III, Hematology and Medical Oncology, University Hospital Regensburg, Regensburg, Germany. Electronic address:

Published: September 2024

Cellular therapies against solid tumors face three major barriers: low persistence, insufficient specificity, and high costs. In a recent study, Pal et al. tackle these challenges in kidney cancer by using novel, 'persistence-tuned' allogeneic chimeric antigen receptor (CAR) T cells directed against a stable antigen.

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http://dx.doi.org/10.1016/j.tips.2024.07.002DOI Listing

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