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Anaemia and iron deficiency in India: a venous blood-based survey of adolescents, adults, and the elderly in eight states.
Eur J Clin Nutr
January 2025
Department of Paediatrics, Sitaram Bhartia Institute of Science and Research, New Delhi, India.
Background: Surveys based on capillary blood show that anaemia is rampant in India, but capillary blood haemoglobin (Hb) may not accurately reflect venous blood Hb concentrations. Further, iron deficiency (ID) is thought to be the main cause of anaemia, there are no venous blood-based surveys to confirm this.
Methods: A community-based (urban, slum and rural) cross-sectional, venous blood survey was conducted in eight Indian states to estimate anaemia and ID prevalences from Hb and inflammation-corrected plasma ferritin concentrations in adolescents, adults, and elderly.
Linked-evidence modelling of qualitative G6PD testing to inform low- and intermediate-dose primaquine treatment for radical cure of Plasmodium vivax.
PLoS Negl Trop Dis
September 2024
Centre for Immunology and Infection Control, Faculty of Health, Queensland University of Technology, Brisbane, Australia.
Background: Radical cure of Plasmodium vivax infections is key to the control of vivax malaria. However, the standard doses of 8-aminoquinoline drugs used for radical cure can cause severe haemolysis in G6PD-deficient patients. The availability of near-patient G6PD tests could increase use of primaquine (PQ), however direct evidence of the impacts that G6PD testing has on downstream patient outcomes, such as haemolysis and recurrence is lacking.
View Article and Find Full Text PDFChild health outcomes and associated factors among under five years children in Ethiopia: a population attributable fractions analysis of Ethiopia demographic and health survey (2005-2016).
BMC Pediatr
September 2024
Center for Population Studies, College of Development Studies, Addis Ababa University, Addis Ababa, Ethiopia.
Introduction: In Ethiopia, more than half (57%) of children aged 6-59 months were estimated to be anemic in 2016 alone. The country had about 37% of under-five children suffering from stunting and under-five mortality rate of 59 deaths per 1000 live births in 2019. The main purpose of this paper was to estimate the proportion of under-five children prevented from childhood undernutrition, anemia, and under-five mortality by removing the risk factors or inequalities.
View Article and Find Full Text PDFEmerging Evidence and Critical Issues with the Use of Single-Drop Capillary Blood for the Measurement of Hemoglobin Concentration in Population-Level Anemia Surveys.
Adv Nutr
October 2024
Program Operations Unit, Nutrition International, Ottawa, Ontario, Canada. Electronic address:
Accurate and precise measurement of hemoglobin concentration is critical for reliable estimations of anemia prevalence at the population level. When systematic and/or random error are introduced in hemoglobin measurement, estimates of anemia prevalence might be significantly erroneous and, hence, limit their usefulness. For decades, single-drop capillary blood has been the most common blood source used for the measurement of hemoglobin concentration in surveys, especially in low-income and middle-income countries.
View Article and Find Full Text PDFPopulation-level anemia prevalence rates may be rendered inaccurate when hemoglobin is measured in pooled capillary blood or with the HemoCue® 301 device.
Int J Lab Hematol
December 2024
Food, Nutrition and Health, Faculty of Land and Food Systems, The University of British Columbia, Vancouver, British Columbia, Canada.
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