The asymmetric Mannich-type reaction of quinoxalin-2-ones with difluoroenoxysilanes has been developed for the synthesis of chiral -difluoroalkylated quinoxalin-2-ones. The reaction worked in the presence of chiral phosphoric acid and B(CF) in THF at room temperature. The reaction exhibited a good substrate scope furnishing the products in good yields (up to 97%) with up to 96% .
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