We examined the effect of preoperative antibiotic exposure and duration on synovial fluid samples from patients with native joint septic arthritis of the hip/knee. While exposure before diagnostic arthrocentesis did not affect fluid parameters, increased duration was associated with a decreased total nucleated cell count, underscoring the complex antibiotic effects on synovial fluid parameters.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11285182PMC
http://dx.doi.org/10.1093/ofid/ofae403DOI Listing

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