What is the dimension of a network? Here, we view it as the smallest dimension of Euclidean space into which nodes can be embedded so that pairwise distances accurately reflect the connectivity structure. We show that a recently proposed and extremely efficient algorithm for data clouds, based on computing first- and second-nearest neighbour distances, can be used as the basis of an approach for estimating the dimension of a network with weighted edges. We also show how the algorithm can be extended to unweighted networks when combined with spectral embedding. We illustrate the advantages of this technique over the widely used approach of characterizing dimension by visually searching for a suitable gap in the spectrum of the Laplacian.
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http://dx.doi.org/10.1098/rsos.230898 | DOI Listing |
J Med Internet Res
January 2025
Learning and Capacity Development Unit, Health Emergencies Programme, World Health Organization, Geneva, Switzerland.
Background: The COVID-19 pandemic demonstrated the global need for accessible content to rapidly train health care workers during health emergencies. The massive open access online course (MOOC) format is a broadly embraced strategy for widespread dissemination of trainings. Yet, barriers associated with technology access, language, and cultural context limit the use of MOOCs, particularly in lower-resource communities.
View Article and Find Full Text PDFBJS Open
December 2024
Department of Cardiology, Thorax Centre, Cardiovascular Institute, Erasmus MC, Rotterdam, The Netherlands.
Background: Contrary to the impact of screening, the effect of long-term surveillance on the quality of life of patients with an abdominal aortic aneurysm is not well known. Therefore, the aim of this study was to describe patient-reported outcomes of patients with an abdominal aortic aneurysm approaching the surgical threshold.
Methods: This multicentre, observational cohort study included patients with an abdominal aortic aneurysm with a maximum aneurysm diameter of greater than or equal to 40 mm.
Agency - the capacity to produce an effect - is a foundational aspect of medical education. Agency is usually conceptualized at the level of the , with each learner charged with taking responsibility to pull themselves up by their bootstraps. This conceptualization is problematic.
View Article and Find Full Text PDFExpert Opin Emerg Drugs
January 2025
Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Introduction: Preclinical and clinical pharmacologic evidence indicate that orexin systems are relevant to sleep-wake cycle regulation and dimensions of reward and cognition, providing the basis to hypothesizing that they may be effective as therapeutics in mental disorders. Due to the limited efficacy and tolerability profiles of existing treatments for Major Depressive Disorder (MDD), investigational compounds in novel treatment classes are needed; seltorexant, an orexin receptor antagonist, is a potential new treatment currently under investigation.
Areas Covered: Mechanisms implicated in MDD, including reward and sleep are first overviewed.
Nanomaterials (Basel)
January 2025
Research Laboratory Neuroelectronics and Memristive Nanomaterials (NEUROMENA Lab), Institute of Nanotechnologies, Electronics and Electronic Equipment Engineering, Southern Federal University, Taganrog 347922, Russia.
This paper presents the results of a study on the formation of nanostructures of electrochemical titanium oxide for neuromorphic applications. Three anodization synthesis techniques were considered to allow the formation of structures with different sizes and productivity: nanodot, lateral, and imprint. The mathematical model allowed us to calculate the processes of oxygen ion transfer to the reaction zone; the growth of the nanostructure due to the oxidation of the titanium film; and the formation of TiO, TiO, and TiO oxides in the volume of the growing nanostructure and the redistribution of oxygen vacancies and conduction channel.
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