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Evaluating the small aperture intraocular lens: depth of focus and the role of refraction and preoperative corneal astigmatism in visual performance. | LitMetric

Evaluating the small aperture intraocular lens: depth of focus and the role of refraction and preoperative corneal astigmatism in visual performance.

J Cataract Refract Surg

From the Summit Eye Care of Wisconsin, Wauwatosa, Wisconsin (Vukich); Vance Thompson Vision, Sioux Falls, South Dakoda; Sanford USD School of Medicine, Sioux Falls, South Dakota (Thompson); Virginia Eye Consultants, Norfolk, Virginia (Yeu); Cleveland Eye Clinic, Elyria, Ohio (Wiley, Bafna); Baylor College of Medicine, Houston, Texas (Koch); Acufocus, Inc., Irvine, California (Lin, Michna).

Published: November 2024

AI Article Synopsis

  • The study aimed to assess depth of focus (DOF) and visual acuities (VAs) in patients undergoing cataract surgery with the IC-8 small aperture intraocular lens (SA IOL) compared to traditional monofocal IOLs.
  • Conducted across 21 sites in the U.S., the one-year clinical trial included cataract patients with mild astigmatism and evaluated outcomes based on different lens types and target refractions.
  • Results showed the SA IOL provided greater binocular and monocular DOF, consistent visual acuity across distances, and effective outcomes for patients with up to 1.5 D of preoperative corneal astigmatism.

Article Abstract

Purpose: To evaluate depth of focus (DOF) and visual acuities (VAs) by manifest refractive spherical equivalent (MRSE) and degree of preoperative corneal astigmatism with the IC-8 small aperture intraocular lens (SA IOL) (Apthera).

Setting: 21 investigational sites in the United States.

Design: Prospective, multicenter, open-label, parallel-group, nonrandomized, examiner-masked, 1-year clinical study.

Methods: Included patients had cataract and ≤1.5 diopters (D) preoperative corneal astigmatism. Patients received either the SA IOL in 1 eye targeted to -0.75 D and a monofocal or monofocal toric IOL in the other targeted to plano (SA IOL group) or bilateral monofocal/monofocal toric IOLs targeted to plano (control group). Monocular and binocular assessments included defocus curves and uncorrected VAs (distance, intermediate, and near) by postoperative MRSE; monocular VAs were assessed by degree of preoperative corneal astigmatism.

Results: The SA IOL group (n = 343) achieved 0.82 D additional binocular DOF vs the control group (n = 110), and SA IOL eyes achieved 0.91 D additional monocular DOF over fellow eyes. Across all MRSEs, the SA IOL group achieved monocular uncorrected VAs of 20/40 or better and binocular uncorrected VAs of 20/32 or better across all distances. In addition, SA IOL eyes with higher (1.0-1.5 D) vs lower (<1.0 D) preoperative corneal astigmatism achieved equivalent monocular uncorrected VAs.

Conclusions: The SA IOL provides increased DOF vs monofocal/monofocal toric IOLs and consistent monocular and binocular vision across several postoperative MRSEs and up to 1.5 D of preoperative corneal astigmatism, giving patients with cataract and mild astigmatism the potential for an extended range of vision and reliable visual outcomes.

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Source
http://dx.doi.org/10.1097/j.jcrs.0000000000001524DOI Listing

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