Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ajog.2024.07.032 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
GenomicGapID: leveraging spatial distribution of conserved genomic sites for broad-spectrum microbial identification.
Microbiol Spectr
March 2025
Department of Emergency Medicine-Adult, University of Michigan, Ann Arbor, Michigan, USA.
Bacterial detection and identification methods can be broadly classified as either untargeted with expansive taxonomic coverage or targeted with narrow taxonomic focus. Untargeted approaches, such as culture and sequencing, are often time-consuming and/or costly, whereas targeted methods, such as PCR, can offer faster and more cost-effective results but require knowledge of the likely pathogen to select the appropriate assay. GenomicGapID, a novel approach that leverages the spatial distribution of conserved genetic regions across microbial genomes, represents a significant advancement in the field of microbial identification.
View Article and Find Full Text PDFIdentification of a Selective Anticancer Agent from a Collection of Complex-And-Diverse Compounds Synthesized from Stevioside.
J Am Chem Soc
March 2025
Department of Chemistry, Cancer Center at Illinois, Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
Compounds constructed by distorting the ring systems of natural products serve as a ready source of complex and diverse molecules, useful for a variety of applications. Herein is presented the use of the diterpenoids steviol and isosteviol as starting points for the construction of >50 new compounds through this complexity-to-diversity approach, featuring novel ring system distortions and a noteworthy thallium(III) nitrate (TTN)-mediated ring fusion. Evaluation of this collection identified as a potent and selective anticancer compound, inducing cell death at low nanomolar concentrations against some cancer cell lines in culture, compared to micromolar activity against others.
View Article and Find Full Text PDFRelAI: an automated approach to judge pointwise ML prediction reliability.
Int J Med Inform
May 2025
Department of Electrical, Computer and Biomedical Engineering, University of Pavia, Italy.
Objectives: AI/ML advancements have been significant, yet their deployment in clinical practice faces logistical, regulatory, and trust-related challenges. To promote trust and informed use of ML predictions in real-world scenarios, reliable assessment of individual predictions is essential. We propose RelAI, a tool for pointwise reliability assessment of ML predictions that can support the identification of prediction errors during deployment.
View Article and Find Full Text PDFInstruct-ReID++: Towards Universal Purpose Instruction-Guided Person Re-identification.
IEEE Trans Pattern Anal Mach Intell
February 2025
Recently, person re-identification (ReID) has witnessed fast development due to its broad practical applications and proposed various settings, e.g., traditional ReID, clothes-changing ReID, and visible-infrared ReID.
View Article and Find Full Text PDFcfDNA Chimerism and Somatic Mutation Testing in Early Prediction of Relapse After Allogeneic Stem Cell Transplantation for Myeloid Malignancies.
Cancers (Basel)
February 2025
John Theurer Cancer Center, 92 Second St., Hackensack, NJ 07601, USA.
: Disease relapse is a primary cause of treatment failure after hematopoietic stem cell transplantation in the treatment of malignancy. Consolidation therapy early after transplantation may reduce this risk, but it is difficult to administer in the setting of various post-transplant complications. We proposed that testing donor cell chimerism and for persistent minimal residual disease (MRD) with next-generation sequencing (NGS) of plasma cell-free DNA (cfDNA) early after transplantation would identify those patients at higher risk of relapse who would possibly benefit from consolidation therapy.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!