Cadmium (Cd) is a hazardous heavy metal known for its detrimental effects on plants, human health, and the environment. This review article delves into the dynamics of Cd uptake, long-distance transport, and its impact on plant performance, with a specific focus on tomato plants. The process of Cd uptake by roots and its subsequent long-distance transport in the xylem and phloem are explored to understand how Cd influences plants operation. The toxic effects of Cd on tomato plants are discussed, highlighting on the challenges it poses to plant growth and development. Furthermore, the review investigates various Cd tolerance mechanisms in plants, including avoidance or exclusion by the root cell wall, root-to-shoot translocation, detoxification pathways, and antioxidative defence systems against Cd-induced stress. In addition, the transcriptomic analyses of tomato plants under Cd stress provide insights into the molecular responses and adaptations of plants to Cd toxicity. Overall, this comprehensive review enhances our understanding of Cd-plant interactions and reveal promising genes for tomato genetic improvement to increase its tolerance to cadmium.
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