Complex odontoma or odontogenic hamartoma is the most common odontogenic tumor, diagnosed mainly in the first two decades of life, rarely exceeding 3 cm. This paper aim is report a clinical case of complex odontoma in the retromolar region that could induce an imminent risk of mandibular fracture. The patient reported local pain, discomfort, an area with hardened edema and absence of the lower right second molar. Using computed tomography, a three-dimensional model was printed and a mandibular reconstruction plate 2.4 mm pre-bent. Through intraoral access, osteotomy was performed to remove the tumor, the tooth and fixation of the plate. With intraoral access, peripheral osteotomy was performed to remove the tumor and the tooth, then fixed a pre-folded plate. The odontogenic hamartoma is a benign and asymptomatic tumor, but can reach large proportions until diagnosed. The surgical planning of large complex odontomas in the mandible must be done with carefull, using technological resources when is possible to help predict the treatment, avoid possible complications, better esthetic result, less invasive procedure and better recovery.
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