A method is proposed for increasing the number of ions during mass-spectrometric analysis of samples in a nonpolar solvent (benzene). For this purpose, aerodynamic thermal breakup droplet ionization (ATBDI) with the impact of β-radiation on the aerosol droplets used in ATBDI was evaluated. This modification of the method, which we named β-ATBDI, allows to shift a nonvolatile analyte (trinitrotoluene in the negative ionization region and cocaine in the positive ionization region, as an example) into a gas phase as an aerosol at room temperature (in contrast to atmospheric pressure chemical ionization). In addition, β-ATBDI enables a researcher to distinguish mass spectrometric peaks of the compounds located in an aerosol droplet from compounds located outside the droplet, i.e., to identify background peaks. Also briefly discussed the ionization of two antibiotics-azithromycin in methylene chloride and sulfadiazine in salt water with β-ATBDI, ATBDI and electrospray ionization source.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.talanta.2024.126573 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
3D modelling and simulation of thermal effects and dispersion of particles carrying infectious respiratory agents in a railway transport coach.
Sci Rep
January 2025
FLUIDIAN, 95450, Commeny, France.
Even though the COVID-19 pandemic now belongs to the long history of infectious diseases that have struck humanity, pathogenic biological agents continue to pose a recurring threat in private places, but also and mainly in places where the public congregates. In our recent research published in this journal in 2022 and 2023, we considered the illustrative example of a commuter train coach in which a symptomatic or asymptomatic passenger, assumed to be infected with a respiratory disease, sits among other travellers. The passenger emits liquid particles containing, for example, COVID-19 virions or any other pathogen.
View Article and Find Full Text PDFNovel numerical and artificial neural computing with experimental validation towards unsteady micropolar nanofluid flow across a Riga plate.
Sci Rep
January 2025
Department of Mechanical Engineering, College of Engineering and Computer Sciences, Jazan University, P.O Box 45124, Jazan, Saudi Arabia.
Fluid flow across a Riga Plate is a specialized phenomenon studied in boundary layer flow and magnetohydrodynamic (MHD) applications. The Riga Plate is a magnetized surface used to manipulate boundary layer characteristics and control fluid flow properties. Understanding the behavior of fluid flow over a Riga Plate is critical in many applications, including aerodynamics, industrial, and heat transfer operations.
View Article and Find Full Text PDFDevelopment of chitosan/hydrolyzed collagen interaction product-based microparticles for the treatment of respiratory tract infections.
Int J Biol Macromol
February 2025
Department of Drug Sciences, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy. Electronic address:
Respiratory tract infections (RTIs) represent a significant global health issue, particularly for vulnerable population, such as children, the elderly, or patients with immunosuppression. In this context, the aim of the present work was the development of Chitosan/Hydrolyzed Collagen-based microparticles (Mps) as a pulmonary drug delivery system (PDDS) for the treatment of RTIs. Mps were produced via spray-drying and composed of chitosan (Cs), one of the most widely used polysaccharides in PDDS, and hydrolyzed collagen (HC), another promising material for the development of PDDS that has not yet been fully explored.
View Article and Find Full Text PDFArticle Synopsis
- Firefighting aircraft are crucial for managing forest fires, but their operations face risks like thermal radiation and changing air dynamics, making safety assessment complex.* -
- The study proposes a framework for analyzing flight safety standards using technical indicators, leading to the establishment of safety criteria related to flight height, speed, and angle of attack.* -
- The research validates a method that quantifies safety constraints, ultimately supporting the development of technical standards for safe aviation operations in fire-fighting scenarios.*
Statistical analysis of periodic MHD chemically radiative casson flow over an inclined cylinder with entropy optimization.
Heliyon
November 2024
Multidisciplinary Action Research (MARS) Lab, Department of Computer Science and Engineering, Daffodil International University, Dhaka, Bangladesh.
Statistical analysis (SA) stands as an indispensable tool in materials science and engineering, aiding in the understanding and optimization of heat and mass transport processes. This study delves into the interplay between periodic magneto-hydrodynamics (MHD) and chemical reactions concerning entropy generation over an inclined porous cylinder (IPC). We employ a statistical approach, amalgamating the robust 6th order Runge-Kutta (R-K) integration algorithm with the Nachtsheim-Swigert (N-S) shooting iteration method, subsequent to converting the governing equations into Ordinary Differential Equation (ODE) form.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!