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Catheter Ablation of Idiopathic Left Anterior Fascicular Ventricular Arrhythmias: Predicting Origin Sites via Mapping and Electrocardiography.
J Cardiovasc Electrophysiol
December 2024
Department of Cardiology, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Background: Idiopathic ventricular arrhythmias (VAs) arising from the left anterior fascicle (LAF) are uncommonly seen, and their characteristics still need to be sufficiently investigated. This study aimed to conclude these VAs' characteristics and explore efficient ablation strategies.
Methods: Data were analyzed from 118 patients undergoing successful catheter ablation for LAF VAs.
"Short", "Long" and "Short-plus-Long'' Coupled Idiopathic Ventricular Fibrillation: Distribution, Demographic and Electrophysiologic Characteristics. A THESIS Substudy.
Heart Rhythm
December 2024
Jesselson Integrated Heart Center, Shaare Zedek Medical Center, Jerusalem, Israel.
An hiPSC-CM approach for electrophysiological phenotyping of a patient-specific case of short-coupled TdP.
Stem Cell Res Ther
December 2024
Department of Medical Physiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Introduction: A healthy young woman, age 26 without prior cardiac complications, experienced an out-of-hospital cardiac arrest caused by ventricular fibrillation (VF), which coincided with a fever. Comprehensive diagnostics including echo, CMR, exercise testing, and genetic sequencing, did not identify any potential cause. This led to the diagnosis of idiopathic VF and installment of an implantable cardioverter defibrillator, which six months later appropriately intervened another VF episode under conditions comparable to the first event.
View Article and Find Full Text PDFEnd-stage heart failure and heart transplant in cardiac sarcoidosis: a case series.
Eur Heart J Case Rep
December 2024
Heart Failure and Transplant Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138 Bologna, Italy.
Article Synopsis
- - Diagnosing cardiac sarcoidosis (CS) is difficult, often leading to heart transplantation (HT) as the last option, especially when immunosuppressive therapies fail in advanced cases.
- - The case study presents four patients, each with different symptoms and backgrounds, who ultimately required HT for their CS, revealing the condition's complexity and urgency.
- - There are significant mid- and long-term challenges following HT for CS, notably the need for careful management of immunosuppression to prevent rejection and recurrence of sarcoidosis.
A potential pathogenic mutation of LAMA4 in a Chinese family with dilated cardiomyopathy and conduction system disease.
Medicine (Baltimore)
December 2024
Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Dilated cardiomyopathy (DCM) is characterized by ventricular dilation and poor systolic function. Approximately half of idiopathic DCM cases are assigned to genetic causes in familial or apparently sporadic cases, and more than 50 genes are reported to cause DCM. However, genetic basis of most DCM patients still keeps unknown and require further study.
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