This study focused on effective methods of laser engraving treatment (LET), plasma spraying, and resin pre-coating (RPC) to manufacture the reinforced adhesive joints of titanium alloy and carbon fiber-reinforced polymer (TA-CFRP) composites. The combined treatments contributed to the creation of a better adhesive bonding condition and offer a vertical gap between circular protrusions to form epoxy pins and carbon nanotube (CNT)-reinforced epoxy pins. The bonding strength of the TA-CFRP composite was reinforced by 130.6% via treatments with a twice-engraving unit of 0.8 mm, plasma spraying, and RPC. The original debonding failure on the TA surface was changed into the cohesive failure of the epoxy adhesive and delamination-dominated failure of the CFRP panel. Overall, laser engraving has been confirmed as an effective and controllable treatment method to reinforce the bonding strength of the TA-CFRP joint combined with plasma spraying and RPC. It may be considered as an alternative in industry for manufacturing high-performance metal-CFRP composites.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11281288 | PMC |
http://dx.doi.org/10.3390/polym16142041 | DOI Listing |
Clin Pharmacol Drug Dev
January 2025
Department of Clinical Pharmacology, Aerospace Center Hospital, Beijing, China.
This study aimed to evaluate the pharmacokinetic characteristics, safety, and bioequivalence of 2 formulations of fluticasone nasal spray in healthy Chinese subjects. A single-center, randomized, open-label, single-dose, 2-formulation, 2-sequence, 2-period crossover bioequivalence study was conducted under fasting conditions. A total of 120 healthy male and female subjects were enrolled, of which 119 subjects completed the entire study.
View Article and Find Full Text PDFMaterials (Basel)
December 2024
The Interdisciplinary Center for Dental Research and Development, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, 19-21 Jean Louis Calderon Street, 020021 Bucharest, Romania.
Tooth loss replacement using dental implants is becoming more frequent. Traditional dental implant materials such as commercially pure titanium and titanium aluminum vanadium alloys have well-proven mechanical and biological properties. New titanium alloying metals such as niobium provide improved mechanical properties such as lower elastic modulus while displaying comparable or even better biocompatibility.
View Article and Find Full Text PDFMaterials (Basel)
December 2024
Joint Institute for High Temperatures, Russian Academy of Sciences, 125412 Moscow, Russia.
This paper presents the initial results of the synthesis of β-GaO luminescent ceramics via plasma gas-thermal spraying synthesis, where low-temperature plasma of an argon and nitrogen mixture was employed. A direct current electric arc generator of high-enthalpy plasma jet with a self-aligning arc length and an expanding channel of an output electrode served as a plasma source. The feedstock material consisted of a polydisperse powder of monocrystalline β-GaO with particle sizes ranging from 5 to 50 μm.
View Article and Find Full Text PDFPol J Vet Sci
September 2024
APC Europe, SLU, Avda. Sant Julià 246-258, P.I. El Congost, 08403, Granollers, Spain.
The effect of feeding spray dried porcine plasma (SDPP) to male turkeys during the first 4 weeks of life was evaluated at 20 weeks of age. A total of 648 male Hybrid Converter day-old turkeys were divided into two groups of 9 replicate pens of 36 birds each, and fed a commercial-type program of 7 diet phases. In phase 1 birds were fed a corn-soybean meal Control diet for 4 weeks, or a diet with 2% SDPP of similar nutrient density.
View Article and Find Full Text PDFFront Pharmacol
November 2024
Phase I Clinical Trial Center, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Background: Intranasal administration is a convenient route for drug delivery that can be applied for procedural sedation. However, there is currently limited exploration into fixed dosing regimens. This study was to investigate the pharmacokinetics (PK), pharmacodynamics (PD), bioavailability (BA) and safety of dexmedetomidine after fixed doses of intranasal and intravenous administration in healthy male and female subjects.
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