In this paper, an alternative and efficient copper(I)-catalyzed synthesis of 2-sulfonyliminocoumarins is developed through a three-component reaction of -hydroxybenzyl alcohol, alkynes, and -toluenesulfonyl azide. The proposed route for access to the 2-iminocoumarin ring involves a [4 + 2] hetero-Diels-Alder reaction between -quinone methide and ketenimine intermediates generated in situ.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11279675 | PMC |
| http://dx.doi.org/10.3390/molecules29143426 | DOI Listing |
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