A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 143

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 143
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 209
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 994
Function: getPubMedXML

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3134
Function: GetPubMedArticleOutput_2016

File: /var/www/html/application/controllers/Detail.php
Line: 574
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 488
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Bacterial Profile and Antimicrobial Resistance Patterns of Diabetic Foot Infections in a Major Research Hospital of Turkey. | LitMetric

AI Article Synopsis

  • Diabetic foot infections (DFIs) are commonly associated with diabetic foot ulcers (DFUs) and often treated with antibiotics, but inappropriate use can lead to increased antibiotic resistance, posing a public health risk.
  • A study in Turkey analyzed 262 patients with DFIs to identify the microbial spectrum and resistance patterns, revealing that 57.60% of isolates were Gram-negative and 41.20% were Gram-positive, with significant resistance rates noted for common pathogens.
  • The findings emphasize the importance of understanding microbial profiles and resistance patterns to assist clinicians in selecting appropriate empirical antibiotic treatments for DFIs.

Article Abstract

Diabetic foot infection (DFI) occurs frequently in patients, followed up with diabetic foot ulcers (DFU). For this reason, antibiotic treatment is often used in patients followed with DFU. Inappropriate use of antibiotics and increasing antibiotic resistance threaten public health. We aimed to investigate the microbial spectrum and antimicrobial resistance patterns isolated from diabetic foot infections in Turkey and help clinicians to choose optimal antibiotics empirically. : This study was planned as a retrospective, single-center, cross-sectional study. Two hundred sixty-two patients whose causative microorganism was isolated in culture of tissue between 1 January 2021 and 31 December 2022 were included in this study. Bacterial profile and antimicrobial resistance patterns were analyzed. Four hundred thirty two isolates from 262 patients isolated in culture of tissue were evaluated. Of these microorganisms, 57.60% were Gram-negative, 41.20% were Gram-positive bacteria, and 1.2% were spp. The most frequently detected Gram-positive microorganism was spp. Gram-negative microorganisms were () and (). Polymicrobial infections were observed in 40.5% of the patients. Methicillin-resistant spp. rate was 51.3%, while extended-spectrum beta-lactamase (ESBL) resistance for was 66.7%. Due to increasing antibiotic resistance rates, treatment of common infections becomes more difficult. Knowledge of the microbiological profile and antibiotic resistance patterns of patients with DFIs is useful to guide empirical therapy.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11274067PMC
http://dx.doi.org/10.3390/antibiotics13070599DOI Listing

Publication Analysis

Top Keywords

resistance patterns
16
diabetic foot
16
antimicrobial resistance
12
antibiotic resistance
12
bacterial profile
8
profile antimicrobial
8
foot infections
8
increasing antibiotic
8
isolated culture
8
culture tissue
8

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!

A PHP Error was encountered

Severity: Notice

Message: fwrite(): Write of 34 bytes failed with errno=28 No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 272

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/lib/php/sessions)

Filename: Unknown

Line Number: 0

Backtrace: