Lactate to albumin ratio as a prognosis predictor in gastrointestinal bleeding in the emergency department.

Intern Emerg Med

Department of Emergency Medicine, Chung-Ang University Gwangmyeong Hospital, College of Medicine, Chung-Ang University, Seoul, 110, Deokan-Ro, Gwangmyeong-Si, Gyeonggi-Do, Republic of Korea.

Published: July 2024

AI Article Synopsis

  • Gastrointestinal bleeding (GIB) is a frequent reason for emergency department visits and has varying outcomes, prompting a study on prognostic measures.
  • The research compared the lactate/albumin (L/A) ratio to the AIMS65 score and blood urea nitrogen/albumin (B/A) ratio in predicting ICU admissions and in-hospital mortality in GIB patients.
  • Results indicated that the L/A ratio was more effective than the other measures, with higher predictive values for ICU admission and mortality, showcasing its potential as a better prognostic tool for GIB patients.

Article Abstract

Gastrointestinal bleeding (GIB) is a common cause of emergency department (ED) visits, and has various prognoses. This study aimed to verify the prognostic ability of the lactate/albumin (L/A) ratio in patients with GIB compared with the AIMS65 score and blood urea nitrogen/albumin (B/A) ratio. This retrospective study included patients with GIB symptoms who visited the ED in 2019. Baseline characteristics and laboratory data were obtained to calculate the L/A and B/A ratios and AIMS65 score. Each score was evaluated as a predictor of intensive care unit (ICU) admission and in-hospital mortality by using the area under the receiver operating characteristic (AUROC) curve. The multivariate logistic regression analysis revealed that the L/A ratio significantly predicted ICU admission and in-hospital mortality. The AUROC curve for predicting ICU admission were 0.788, 0.695, and 0.586 for the L/A, B/A, and AIMS65 scores, respectively, while the AUROC curve for predicting in-hospital mortality were 0.807, 0.799, and 0.683 for the L/A, B/A, and AIMS65 scores, respectively. The L/A ratio, which consists of the serum lactate and albumin levels, showed superior performance relative to the B/A ratio and AIMS65 score in predicting the prognosis of patients with GIB.

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Source
http://dx.doi.org/10.1007/s11739-024-03723-3DOI Listing

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