To the trained eye, every tooth is different. An in-depth understanding of dental anatomy in cross-sectional images is a fundamental basic skill required when interpreting cone beam computed tomography (CBCT) scans. The conventional orthogonal planes of axial, coronal, and sagittal are not always the best planes in which to assess teeth because every tooth is at a slightly different angle to all these planes. In this chapter, the author demonstrates the characteristic anatomy of upper and lower incisors, canines, premolars, and molars in longitudinal and transverse sections, using carefully uprighted images. Some of these teeth are also shown in transverse section at various levels in the crown and root. The chronology of permanent teeth is shown. Developing teeth are discussed and incremental growth lines are mentioned.The author describes three well-known dental notation systems (Palmer, FDI, hybrid).There are four videos accompanying this chapter, including one fascinating video showing a scroll-through of all the cross-arch sections of a synthetic panoramic (curved multiplanar reconstruction) image that includes all the upper and lower teeth in a 16-year-old.
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http://dx.doi.org/10.1038/s41415-024-7568-4 | DOI Listing |
J Exp Clin Cancer Res
January 2025
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Background: Glioblastoma (GBM) is a lethal brain tumor characterized by the glioma stem cell (GSC) niche. The V-ATPase proton pump has been described as a crucial factor in sustaining GSC viability and tumorigenicity. Here we studied how patients-derived GSCs rely on V-ATPase activity to sustain mitochondrial bioenergetics and cell growth.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Department of Maxillofacial Pathology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: Aurora kinase A (AurkA) plays a vital role in mitosis and is therefore critical in tumors development and progression. There are a few studies on AurkA expression in salivary gland tumors. The aim of the present study was to evaluate the expression pattern of AurkA in the most common benign and malignant salivary gland tumors by immunohistochemistry.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Maxillofacial Surgery and Diagnostic Science, College of Dentistry, Qassim University, Buraydah, Saudi Arabia.
Background: In dentistry, local anesthetic is frequently used to manage pain throughout several phases of dental treatments, including tooth extraction. The study aimed to compare the effectiveness of two techniques for controlling pain during mandibular exodontia (tooth extraction), specifically focusing on the pain experienced during injection and extraction of mandibular anterior and premolars teeth. The two techniques being compared are the intraligamentary injection technique (ILI) and the incisive nerve block technique (INB).
View Article and Find Full Text PDFCommun Biol
January 2025
Nanfang Hospital, Southern Medical University, Guangzhou, China.
Dental pulp regeneration is significantly aided by human dental pulp stem cells (hDPSCs). An increasing number of studies have demonstrated that circular RNAs (circRNAs) are crucial in the multidirectional differentiation of many mesenchymal stem cells, but their specific functions and mechanisms remain unknown. This work aimed at elucidating the molecular mechanism by which hsa_circ_0001599 works in hDPSCs during odontogenic differentiation.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, 600077, India.
Polydopamine (PD), inspired by the wet adhesion mechanism of mussel foot proteins, has emerged as a promising adhesive material with wide-ranging applications. This study aimed to compare the adhesive properties of PD and Glass Ionomer Cement (GIC) on enamel and dentin substrates, evaluating PD's potential as an alternative adhesive in dental practice. A total of 120 human premolars were prepared, with 80 teeth allocated for Scanning Electron Microscopy (SEM) analysis and 40 teeth reserved for shear bond strength testing.
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