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Acute Quadriparesis: A Rare Presenting Manifestation of an Adrenal Tumor.
Cureus
September 2024
Radiodiagnosis, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Article Synopsis
- Acute quadriparesis was seen in a 54-year-old woman with sudden weakness in all limbs, prompting extensive investigation due to its serious nature.
- Initial tests showed low potassium levels (hypokalemia), which were treated with IV potassium, leading to improved strength; potential causes like Guillain-Barré syndrome were ruled out.
- Imaging revealed an adrenal tumor, and after surgery to remove it, the patient fully recovered, highlighting the need to consider endocrine disorders in similar cases and the importance of thorough diagnosis and management.
Article Synopsis
- A 52-year-old male developed severe weakness and was hospitalized due to hypokalemia and rhabdomyolysis after increasing his chlorthalidone dosage from 25 mg to 50 mg daily.
- Extensive testing eliminated other potential causes of his hypokalemia, indicating it was likely due to the medication.
- The patient's condition improved significantly with potassium supplementation and stopping the chlorthalidone, highlighting the need for awareness about serious side effects of diuretics even with minor dose adjustments.
Spontaneous Adrenal Hemorrhage in a Pregnant Woman With Glucocorticoid Resistance Syndrome.
JCEM Case Rep
April 2024
Department of Endocrinology, Seth G.S. Medical college and KEM Hospital, Mumbai 400012, India.
Glucocorticoid resistance syndrome is a rare disorder with no genetically proven cases reported from India; in addition, there are no descriptions available regarding its management during pregnancy. A 27-year-old woman, hypertensive since the age of 17 years, presented with hypokalemic paresis. She reported regular menses and acne.
View Article and Find Full Text PDFCardiovascular Remodeling in Chronic Mineralocorticoid Excess.
Cureus
June 2023
Cardiovascular Medicine, Saint Vincent Hospital, UMass Chan Medical School, Worcester, USA.
Primary hyperaldosteronism typically leads to resistant hypertension, hypokalemia, and metabolic alkalosis. Excess aldosterone secretion by the adrenal glands may lead to heart failure with preserved ejection fraction. Potassium-sparing diuretics and aldosterone antagonists directed to lower excess aldosterone levels may help treat the associated heart failure and lead to control of blood pressure, resulting in improved outcomes.
View Article and Find Full Text PDFCase report: Gitelman syndrome with diabetes: Confirmed by both hydrochlorothiazide test and genetic testing.
Medicine (Baltimore)
June 2023
Department of Endocrinology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China.
Rationale: Gitelman syndrome (GS) is an autosomal recessive tubulopathy caused by mutations of the SLC12A3 gene. It is characterized by hypokalemic metabolic alkalosis, hypomagnesemia and hypocalciuria. Hypokalemia, hypomagnesemia, and increased renin-angiotensin-aldosterone system (RAAS) activity can cause glucose metabolism dysfunction.
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