AI Article Synopsis
- Human pluripotent stem cell technologies are now widely used in biomedical research for studying early human development, disease, drug screening, and cell therapies for difficult diseases.
- The advancements driving this revolution come from various fields such as cancer biology, reproductive technologies, cell culture, and gene editing.
- The review discusses the gradual development of human pluripotency studies and highlights the rapid expansion of the field over recent decades.
Article Abstract
Today, human pluripotent stem cell technologies find widespread application across biomedical research, as models for early human development, as platforms for functional human genomics, as tools for the study of disease, drug screening and toxicology, and as a renewable source of cellular therapeutics for a range of intractable diseases. The foundations of this human pluripotent stem cell revolution rest on advances in a wide range of disciplines, including cancer biology, assisted reproduction, cell culture and organoid technology, somatic cell nuclear transfer, primate embryology, single-cell biology, and gene editing. This review surveys the slow emergence of the study of human pluripotency and the exponential growth of the field during the past several decades.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/bies.202400092 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!