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Uncommon Millettia pachycarpa Benth poisoning: A case report. | LitMetric

AI Article Synopsis

  • Millettia pachycarpa Benth can cause serious poisoning due to its rotenone content, leading to respiratory and central nervous system issues, and potentially death.
  • A case study reports on an elderly male who lost consciousness for 3 hours after eating the fruit, showing serious blood gas imbalances indicating poisoning.
  • The patient received advanced treatment including continuous renal replacement therapy and mechanical ventilation, and after 5 days in the hospital, he was discharged without significant issues, highlighting the importance of quick intervention in such poisonings.

Article Abstract

Background: Millettia pachycarpa Benth, rich in rotenone, can disrupt the mitochondrial electron transport chain. Ingestion may cause respiratory and central nervous system depression, and in severe cases, lead to death. This is the first detailed clinical case report of M. pachycarpa Benth poisoning, aiming to help systematization of diagnosis and treatment.

Patient Concerns: An elderly male who lost consciousness for 3 hours after consuming the fruit of M. pachycarpa Benth. Arterial blood gas analysis indicated a significant decrease in pH, a sharp increase in lactate levels, and elevated CO2 partial pressure with normal O2 partial pressure.

Diagnosis: The patient was diagnosed with food intoxication by M. pachycarpa Benth, concomitant with aspiration pneumonia and distributive shock.

Interventions: The patient was given continuous renal replacement therapy (CRRT) and invasive mechanical ventilation.

Outcomes: The patient was successfully discharged after 5 days of hospitalization. Follow-up after 2 weeks showed no significant discomfort.

Conclusion: Isolated CO2 retention without hypoxemia, significantly reduced pH, and markedly elevated lactate levels strongly suggest poisoning by M. pachycarpa Benth. CRRT and invasive mechanical ventilation are beneficial for patients. Early implementation of CRRT to remove toxins and early initiation of assisted ventilation to improve respiratory failure are recommended upon suspicion of the disease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11272360PMC
http://dx.doi.org/10.1097/MD.0000000000038967DOI Listing

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