The spline reconstruction technique (SRT) is a fast algorithm based on a novel numerical implementation of an analytic representation of the inverse Radon transform. The purpose of this study was to compare the SRT, filtered back-projection (FBP), and the Tera-Tomo 3D algorithm for various iteration numbers, using small-animal dynamic PET data obtained from a Mediso nanoScan PET/CT scanner. For this purpose, Patlak graphical kinetic analysis was employed to noninvasively quantify the myocardial metabolic rate of glucose (MRGlu) in seven male C57BL/6 mice (n=7). All analytic reconstructions were performed via software for tomographic image reconstruction. The analysis of all PET-reconstructed images was conducted with PMOD software (version 3.506, PMOD Technologies LLC, Fällanden, Switzerland) using the inferior vena cava as the image-derived input function. Statistical significance was determined by employing the one-way analysis of variance test. The results revealed that the differences between the values of MRGlu obtained via SRT versus FBP, and the variants of he Tera-Tomo 3D algorithm were not statistically significant ( > 0.05). Overall, the SRT appears to perform similarly to the other algorithms investigated, providing a valid alternative analytic method for preclinical dynamic PET studies.
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http://dx.doi.org/10.3390/jimaging10070170 | DOI Listing |
J Neural Eng
December 2024
University of California San Francisco, 513 Parnassus Avenue, S362, SAN FRANCISCO, San Francisco, 94143, CHINA.
Objective: Electroencephalography (EEG) and Magnetoencephalography (MEG) are widely used non-invasive techniques in clinical and cognitive neuroscience. However, low spatial resolution measurements, partial brain coverage by some sensor arrays, as well as noisy sensors could result in distorted sensor topographies resulting in inaccurate reconstructions of underlying brain dynamics. Solving these problems has been a challenging task, This paper proposes a robust framework based on electromagnetic source imaging for interpolation of unknown or poor quality EEG/MEG measurements.
View Article and Find Full Text PDFJ Craniofac Surg
December 2024
Department of Surgery, Division of Plastic and Reconstructive Surgery, Mayo Clinic.
Objective: The pattern, rate, and natural history of bone flap resorption following cranioplasty with frozen, autologous bone flap has not been fully defined. The authors sought to quantify the progression and natural history of bone flap resorption.
Methods: Patients who had craniectomy and delayed cranioplasty with stored, frozen bone flap between 2012 and 2022 were included in this study.
Environ Technol
November 2024
School of Civil Engineering, Shenyang Jianzhu University, Shenyang, People's Republic of China.
BMC Oral Health
November 2024
Departments of Periodontology and Oral Basic Science, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction & Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou Medical University, Guangzhou, China.
Objectives: To explore the association between hyperuricemia and having periodontitis.
Materials And Methods: A representative cross-sectional dataset of 10,158 adults was extracted from the National Health and Nutrition Examination Survey (NHANES) 2009-2014. The association between hyperuricemia (the primary exposure) and having periodontitis (outcome) were evaluated using weighted logistic regression models.
Breast
October 2024
Department of Health Technology and Services Research, Technical Medical Centre, University of Twente, Enschede, the Netherlands; Department of Research and Development, Netherlands Comprehensive Cancer Organisation (IKNL), Utrecht, the Netherlands.
Background: Individual risk prediction of 5-year locoregional recurrence (LRR) and contralateral breast cancer (CBC) supports decisions regarding personalised surveillance. The previously developed INFLUENCE tool was rebuild, including a recent population and patients who received neoadjuvant systemic therapy (NST).
Methods: Women, surgically treated for nonmetastatic breast cancer, diagnosed between 2012 and 2016, were selected from the Netherlands Cancer Registry.
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