Biomechanical tests typically involve bending, compression, or shear stress, while fall tests are less common. The main challenge in performing fall tests is the non-reproducible directionality of bone when tested with soft tissue. Upon removal of the soft tissue, the explanted bone's resistance to impact diminishes. Therefore, ballistic gels can fix specimens in reproducible directions and simulate periosteal soft tissue. However, the use of ballistic gels in biomechanical studies is neither standardized nor widespread. This study aimed to optimize a ballistic gel consistency that mimics the upper thigh muscle in sheep. Our results suggest a standardized and flexible evaluation method by embedding samples in ballistic gel. Compression tests were conducted using cylindrical pieces of gluteal muscle from sheep. Various compositions of agarose and gelatin mixtures were tested to achieve a muscle-like consistency. The muscle-equivalent ballistic gel was found to consist of 29.5% gelatin and 0.35% agarose. Bones remained stable within the ballistic gel setup after freeze-thaw cycles between -20 °C and +20 °C. This method reduces the variability caused by muscle and improves storage quality, allowing for tests to be conducted under consistent conditionsBallistic gels of agarose and gelatin are suitable for bone fracture models. They have muscle-like strength, fix fractures simultaneously, are inexpensive to produce, and can be stored to allow repeated measurements of the same object with changing questions.
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http://dx.doi.org/10.3390/gels10070461 | DOI Listing |
IEEE Sens J
April 2024
Department of Mathematics and the School of Biomedical Engineering, Colorado State University, Fort Collins, CO 80523 USA.
Pulmonary imaging with ultrasound in the conventional MHz range suffers from significant artifacts, as the high frequency acoustic waves primarily reflect off of the lung pleura with little to no penetration through the lung tissue. Furthermore, B-mode ultrasound images are difficult to interpret and require a skilled technician to obtain. Motivated by the finding that acoustic frequencies in the kHz penetrate lung tissue, a low-frequency tomographic ultrasound system is presented.
View Article and Find Full Text PDFJ Vet Med Educ
March 2024
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, 1800 Christensen Dr., Ames, IA 50011.
Diagnostic ultrasound is an important imaging modality in veterinary medicine. Surveys of veterinarians suggest that ultrasound is a desired clinical competence and that new graduates are expected to practice basic ultrasound skills. This report describes the development and implementation of a basic ultrasound training program in the core curriculum at Iowa State University College of Veterinary Medicine (ISU-CVM).
View Article and Find Full Text PDFInterv Pain Med
September 2024
Department of Rehabilitation Medicine, Cornell University Medical Center, USA.
Appl Radiat Isot
January 2025
Nuclear Engineering Department. Federal University of Minas Gerais, 31.270-901, Belo Horizonte, Minas Gerais, Brazil; Nuclear Technology Development Center, 31.270-901, Belo Horizonte, Minas Gerais, Brazil.
Whole-body counter (WBC) systems are used for in vivo monitoring in occupational internal dosimetry, typically calibrated using physical anthropomorphic phantoms. Our research group previously 3D-printed the Reference Female Phantom for Internal Dosimetry (RFPID) without internal organs specifically designed for WBC calibration. The RFPID and it is intended to fill it homogenously with ballistic gel, which is commonly used as a tissue equivalent in ballistic studies.
View Article and Find Full Text PDFACS Nano
September 2024
Department of Biomedical Engineering, College of Engineering, University of Arkansas, Fayetteville, Arkansas 72701, United States.
This study evaluates the use of poly(vinyl alcohol), collagen, and chitosan blends for developing a microneedle patch for the delivery of meloxicam (MEL). Results confirm successful MEL encapsulation, structural integrity, and chemical stability even after ethylene oxide sterilization. Mechanical testing indicates the patch has the required properties for effective skin penetration and drug delivery, as demonstrated by load-displacement curves showing successful penetration of pig ear surfaces at 3N of normal load.
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