AI Article Synopsis
- Metabolic and endocrine issues in white adipose tissue (WAT) are connected to inflammation, which is a major cause of insulin resistance (IR).
- New research suggests that there are also non-inflammatory factors contributing to IR in WAT, which could potentially initiate inflammation.
- These findings open up new strategies for addressing IR by focusing on these non-inflammatory mechanisms rather than just inflammation itself.
Article Abstract
Metabolic and endocrine dysfunction of white adipose tissue (WAT) is linked to inflammation, which has been considered a key mechanism of insulin resistance (IR). However, recent studies revealed non-inflammatory mechanisms of IR in WAT, which may trigger inflammation and could be developed as a novel strategy to counteract IR.
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| http://dx.doi.org/10.1016/j.tips.2024.06.008 | DOI Listing |
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