AI Article Synopsis
- The COVID-19 pandemic has been labeled the deadliest disease event, with about 50,000 deaths in the Netherlands from 2020-2022, compared to 32,000 from the Spanish flu between 1918-1920.
- However, the crude mortality rates indicate that Spanish flu was actually deadlier, with 486 deaths per 100,000 compared to 287 for COVID-19.
- When adjusting for population differences, the study shows that the Spanish flu likely had higher age-standardized mortality rates than COVID-19, suggesting it was more lethal overall.
Article Abstract
The coronavirus disease 2019 (COVID-19) pandemic has been called the deadliest disease event in history. In this study, we compared the cause-specific mortality rate of the Spanish flu (1918-1920) with that of COVID-19 (2020-2022) in the Netherlands. During the periods of exposure, about 50 000 people died of COVID-19 and 32 000 people of the Spanish flu. In absolute numbers, COVID-19 seems to be deadlier than Spanish flu. However, the crude mortality rates for COVID-19 and Spanish flu were 287 and 486 per 100 000 inhabitants, respectively. Comparing age-standardized mortality rates, there would have been 28 COVID-19- and 194 Spanish flu-related deaths in 1918-1920, or 214 Spanish flu- and 98 COVID-19-related deaths in 2020-2022 per 100 000 inhabitants per year. Thus, taking the population differences into account, the Spanish flu would have been deadlier than COVID-19.
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| http://dx.doi.org/10.1093/infdis/jiae071 | DOI Listing |
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