A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionu2h3c95se6gcjut6thdmhb0rkcim6323): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

Neonatal Graves Disease Masquerading as Hemochromatosis. | LitMetric

Neonatal Graves Disease Masquerading as Hemochromatosis.

JCEM Case Rep

Riley Hospital for Children, Division of Pediatric Endocrinology & Diabetology; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

Published: July 2024

Thyroid autoimmunity is extremely common in the adult population and can affect pregnancy outcomes. Signs in the newborn can range from absent to severe, making the diagnosis easy to miss. We present an interesting case of neonatal Graves disease associated with intrauterine growth restriction, premature delivery, and liver failure with severely high ferritin, thought to be secondary to hemochromatosis. Treatment of the underlying hyperthyroidism caused a rapid resolution of the elevated ferritin and liver failure. This report highlights the importance of considering Graves disease in newborns with liver failure of unknown etiology.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11267223PMC
http://dx.doi.org/10.1210/jcemcr/luae132DOI Listing

Publication Analysis

Top Keywords

graves disease
12
liver failure
12
neonatal graves
8
disease masquerading
4
masquerading hemochromatosis
4
hemochromatosis thyroid
4
thyroid autoimmunity
4
autoimmunity extremely
4
extremely common
4
common adult
4

Similar Publications

Previous studies have suggested a comorbidity between autoimmune thyroid disease (AITD) and urticaria. However, the causal effects between AITD and urticaria remain unclear. This study employed genome-wide association study (GWAS) data to analyze the associations between AITD and urticaria through bidirectional Mendelian randomization (MR), meanwhile, examined the role of 731 immune traits as mediators between the two diseases through mediation analysis.

View Article and Find Full Text PDF

Autoimmune thyroid disease is a risk factor for mood disorders, a Mendelian randomization study.

J Affect Disord

March 2025

Department of Thyroid Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun 130021, China. Electronic address:

Background: Observational studies have demonstrated associations between autoimmune thyroid disease and both mood disorders and dementia, but the direction of causality has not been established.

Methods: We employed bidirectional, two-sample Mendelian randomization analyses to assess the causal links between autoimmune thyroid disease (Graves' disease and autoimmune thyroiditis), and mood disorders (major depressive disorder and bipolar disorder) as well as dementia (Alzheimer's disease and dementia with Lewy bodies). We obtained Genome-Wide Association Study data from the Finngen database and IEU Open GWAS.

View Article and Find Full Text PDF

The von Gräfe sign measurement.

Orbit

March 2025

Department of Ophthalmology, School of Medicine de Ribeirão Preto, University of São Paulo, Ribeirao Preto, Brazil.

Purpose: To measure the amplitude of upper eyelid saccadic movements in patients with Graves' retraction.

Methods: The amplitude and velocity of lid saccades were quantified using customized software in 36 patients with Graves' upper eyelid retraction (GO) and in 32 subjects of a control group (CG). All patients were in the chronic phase of the disease and had a controlled thyroid status.

View Article and Find Full Text PDF

Introduction: the indication for pancreatic necrosectomy arises in a context of seriousness. Several factors can influence postoperative outcomes. Our objective is to identify the clinical and paraclinical factors which would influence the occurrence of complications after pancreatic necrosectomy.

View Article and Find Full Text PDF

Complement C5/C5a in the diagnosis and treatment of Graves ophthalmopathy: A Mendelian randomized study.

Zhong Nan Da Xue Xue Bao Yi Xue Ban

October 2024

Department of Ophthalmology, Third Xiangya Hospital, Central South University, Changsha 410013, China.

Objectives: Graves' ophthalmopathy is a complex organ-specific autoimmune disease with an unclear pathogenesis. Complement component 5/5a (C5/C5a), a key element of the component system, may play a significant role in the disease's pathological process. This study aims to investigate the causal relationship between C5/C5a and Graves' ophthalmopathy using Mendelian randomization (MR) to provide new theoretical insights for its diagnosis and treatment.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!