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[Hepatic iron overload].
Ann Pathol
November 2024
Anatomie pathologique, hôpital Pontchaillou, CHU, 35003 Rennes, France.
Article Synopsis
- Iron is crucial for cell and overall body function, and Perls staining helps identify iron deposits in tissues.
- Hepatic siderosis can be classified into three types: parenchymal, mesenchymal, or mixed, aiding in understanding its causes.
- HFE1 hemochromatosis, the most prevalent form of siderosis, is diagnosed through genetic testing, and the presence of hepatic siderosis might indicate its occurrence, despite variability in expression and incomplete penetrance.
[Compensation of occupational diseases during monitoring of the ARDCO cohort].
Rev Mal Respir
September 2024
Équipe GEIC20, Inserm, U955, Créteil, France; Service de pathologies professionnelles et de l'environnement, institut santé-travail Paris-Est, centre hospitalier intercommunal de Créteil, Créteil, France.
Introduction: Questions concerning under-reporting of occupational diseases (OD) linked to asbestos exposure are regularly voiced in France. Monitoring of the French multicenter Asbestos-Related Disease Cohort (ARDCO), which ensures post-occupational medical surveillance of subjects having been exposed to asbestos, provides information on (1) the medico-legal steps taken following screening by computed tomography (CT) for benign thoracic diseases, and (2) recognition of OD as a causal factor in malignant diseases.
Methods: OD recognition - and possible compensation - was analyzed in July 2021 among 13,289 volunteers in the cohort recruited between 2003 and 2005.
Quality of life in retired workers with past exposure to asbestos.
Am J Ind Med
July 2024
INSPIIRE, Université de Lorraine, Inserm, Nancy, France.
Article Synopsis
- - The study investigates the health-related quality of life (HRQoL) of retired men exposed to asbestos, focusing on how perceived risks and respiratory symptoms impact their well-being.
- - Researchers analyzed questionnaires from 1,266 retired workers, finding that a higher perceived risk of asbestos exposure correlated with lower scores in both physical and mental health components.
- - The presence of respiratory symptoms was significantly linked to decreased HRQoL, while expert assessments of asbestos exposure didn't show a direct impact on health outcomes.
Systemic sclerosis, silica exposure and cellular therapies: The sand in the gears?
Rev Med Interne
July 2024
Unité de médecine interne (UF04): CRMR MATHEC, maladies auto-immunes et thérapie cellulaire, centre de référence des maladies auto-immunes systémiques rares d'Île-de-France, recherche clinique en hématologie, immunologie et transplantation, URP3518, hôpital St-Louis, AP-HP, université Paris Cité, IRSL, 75010 Paris, France; Department of Medicine, McGill University, H3A 1A1 Montreal, Canada.
Systemic sclerosis (SSc) is a chronic orphan autoimmune disease with the highest mortality rate among rheumatic diseases. SSc-related interstitial-lung disease (ILD) remains among the leading causes of SSc-related mortality with still few therapeutic effective strategies. In patients with crystallin silica exposure, SSc is recognized as an occupational disease according to the French social security system (Table 25A of the general insurance regimen).
View Article and Find Full Text PDF[Not Available].
CMAJ
February 2024
Air Pollution Exposure Laboratory (Carlsten), Faculté de médecine, Université de la Colombie-Britannique, Vancouver, C.-B.; Division de pneumologie (McCauley), Faculté de médecine, Université de la Colombie-Britannique, Kelowna, C.-B.; École de médecine (Loss), Université de Limerick, Limerick, Irlande.
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